a recorded nerve signal via an electrode is composed of many evokes or action potentials, (originated from individual axons) which may be considered as different initial sources. recovering these primitive sources in its turn may lead us to the anatomic originations of a nerve signal which will give us outstanding foresights in neural rehabilitations. accordingly, clinical interests may be r...

Submit Manuscript | http://medcraveonline.com Abbreviations: ASFA: American Society for Apheresis; CMAPs: Compound Muscle Action Potentials; CSF: Cerebrospinal Fluid; EEG: Electroencephalogram; EMG: Electromyogram; EVM: Eye opening, Verbal response, Motor response; GBS: Guillain Barré Syndrome; GCS: Glasgow Coma Scale; IVIG: Intravenous Immunoglobulin; NCS: Nerve Conduction Study; NMICU: NeuroM...

A method for recording the medial plantar sensory nerve action potential at the ankle with surface electrodes is described. Normal values in 69 control subjects are given and compared with the sural sensory nerve action potential in the same limb in the same subjects. Clinical applications were studied in 33 patients. The procedure may be applied in the diagnosis of L4-5 nerve plexus or root le...

OBJECTIVES The aim of this study was to investigate whether tramadol had a dose-dependent blocking effect on nerve conduction when administered perineurally to the sural nerve of healthy volunteers. METHODS Twenty-four informed healthy subjects were randomized into four equal groups [Saline (placebo), 0.5% tramadol, 1% tramadol and 1.5% tramadol]. The study was designed to be double-blinded. ...

The peroneal nerve anatomy of the rabbit distal hindlimb is similar to humans, but reports of distal peroneal nerve conduction studies were not identified with a literature search. Distal sensorimotor recordings may be useful for studying rabbit models of length-dependent peripheral neuropathy. Surface electrodes were adhered to the dorsal rabbit foot overlying the extensor digitorum brevis mus...

Somatic sensation requires the conversion of physical stimuli into the depolarization of distal nerve endings. A single cRNA derived from sensory neurons renders Xenopus laevis oocytes mechanosensitive and is found to encode a P2Y1 purinergic receptor. P2Y1 mRNA is concentrated in large-fiber dorsal root ganglion neurons. In contrast, P2X3 mRNA is localized to small-fiber sensory neurons and pr...

It has been shown by Dawson and Scott (1949) that when the median or ulnar nerve is stimulated with a brief shock at the wrist an action potential can be recorded from the nerve at a higher level in the arm through electrodes placed on the skin over the course of the nerve. This technique has proved to be of considerable practical value in the assessment of patients with ulnar nerve lesions at ...

Median nerve sensory fibres were stimulated with minimal and supramaximal stimuli at the base of the third digit in 30 normal subjects. Evoked nerve action potentials were simultaneously recorded from two points on the median nerve just above the wrist. As stimulus voltage was increased from minimal to supramaximal, amplitudes of nerve action potentials increased, latencies decreased, but condu...

INTRODUCTION Sensory chronic inflammatory demyelinating polyneuropathy (CIDP) can be difficult to diagnose. METHODS We report 22 patients with chronic sensory polyneuropathy with ≥1 clinical sign atypical for chronic idiopathic axonal polyneuropathy (CIAP) but no electrodiagnostic criteria for CIDP. RESULTS Clinical signs atypical for CIAP were: sensory ataxia (59%), generalized areflexia (...