Sepsis is a severe inflammatory disease resulting in excessive production of pro-inflammatory cytokines including interleukin-6 (IL-6), causing oxidative stress, tissue damage and organ dysfunction. Health benefits have been observed upon selenium (Se) supplementation in severe sepsis. Selenium is incorporated into selenoproteins implicated in anti-oxidative defence, thyroid hormone metabolism ...

We present a Secure E-commerce Protection Profile (SEPP) that captures security requirements for securing sessions in the e-commerce operational environment. The SEPP is prepared in accordance with the Common Criteria (CC), Version 2.1, as specified by the ISO 15408 standard. The SEPP states the requirements that sessions must satisfy in order to respond to the needs of e-commerce. The Target o...

Selenium (Se) is an essential trace element for selenoprotein biosynthesis. Selenoproteins have been implicated in cancer risk and tumor development. Selenoprotein P (SePP) serves as the major Se transport protein in blood and as reliable biomarker of Se status in marginally supplied individuals. Among the different malignancies, renal cancer is characterized by a high mortality rate. In this s...

Sport, Exercise, and Performance Psychology (SEPP), the official journal of Division 47 (Society for Sport, Exercise & Performance Psychology) of the American Psychological Association (APA), is now in its sixth year of publication. Jeff Martin, the first Editor, has done a fantastic job in establishing SEPP as one of the leading journals in the field of sport, exercise, and performance psychol...

OBJECTIVE It is still a matter of debate if subtle changes in selenium (Se) status affect thyroid function tests (TFTs) and bone mineral density (BMD). This is particularly relevant for the elderly, whose nutritional status is more vulnerable. DESIGN AND METHODS We investigated Se status in a cohort of 387 healthy elderly men (median age 77 yrs; inter quartile range 75-80 yrs) in relation to ...

The self-exciting point process (SEPP) model has recently been shown to perform well in predicting spatiotemporal crime patterns. However, this model has not been widely applied to crime data and many open questions remain about how best to implement it in a real setting. In this work, we consider a range of practical implementation details relating to the application of SEPP models to real cri...

How is the essential micronutrient, selenium (Se), transported in the serum and then donated to tissues? In this issue of the Biochemical Journal, Schweizer and colleagues demonstrate, using conditional and total mouse knockout models, that SePP (selenoprotein P) is the major transporter of Se in the serum. Moreover, in the sanctuary area of the brain, SePP was shown to play a hitherto unexpect...

I. Domsik P, Kalapos A, Chadaide S, Forster T, Sepp R, Nemes A. Evaluation of left atrial function in hypertrophic cardiomyopathy by volumetric and strain analysis –