Rheumatoid factor became the first laboratory marker of rheumatoid arthritis and one serological markers used to recognize major autoimmune diseases. Details discovery with special regard contribution E. Waaler H. Rose are presented in this historical review. Same assays exam factor, its frequency modern view on diagnostic significance different diseases described article.

Background Evaluation of serological assays for hepatitis C (HCV) antibody screening is crucial ,as supplemental testing [Nucleic Acid Testing & Recombinant Immunoblot Assay (RIBA)] to verify anti-HCV reactive results is not widely practiced, due to limited availability and high cost. The current study was undertaken from January to May 2011, to evaluate 4 serological assays for HCV diagnosis, ...

An extensive range of serological and molecular diagnostic assays exist for most of the economically important Theileira species such as T. annulata, T. equi, T. lestoquardi, T. parva, T. uilenbergi and other more benign species. Diagnostics of Theileria is considered with regard to sensitivity and specificity of current molecular and serological assays and their use in epidemiology. In the cas...

Visceral leishmaniasis (VL) is a zoonotic disease caused by leishmania species. Dogs are considered to be the main reservoir of VL. A number of methods and antigen-based assays are used for the diagnosis of leishmaniasis. However, currently available methods are mainly based on direct examination of tissues for the presence of parasites, which is highly invasive. A variety of serological tests ...

Patients with chronic inflammatory diseases are often treated immunosuppressants and therefore of particular concern during the SARS-CoV-2 pandemic. Serological tests will improve our understanding infection immunity in this population, unless they give false positive results. The aim study was to evaluate specificity SARS-Cov-2 serological assays using samples from patients collected prior Apr...