Introduction. The presence of a serous cyst in the tympanic membrane implies the description of a new or unpublished entity based on our knowledge whose origin may be very unlikely explained on actual embryologic and anatomic background. Clinical Case. We present a case of a 45-year-old woman with progressing right hearing loss. Physical examination revealed a whitish, round-shaped malformation...

The serous acini of airway submucosal glands are important for fluid secretion in the lung. Serous cells are also sites of expression of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel. However, the mechanisms of serous cell fluid secretion remain poorly defined. In this study, serous acinar cells were isolated from porcine bronchi and studied using optical techniqu...

The characteristic cutaneous rheumatoid nodule, described fully by Collins (1937) and Bennett, Zeller, and Bauer (1940), is composed of a central area of fibrinoid necrosis around which develops an encircling corona of closely packed mesenchymal cells, the great majority of which appear to be fibroblasts (Collins, 1937), and external to this is a zone of inflammatory tissue. Lesions with simila...

Serous cells secrete Cl(-) and HCO(3)(-) and play an important role in airway function. Recent studies suggest that a Cl(-)/HCO(3)(-) anion exchanger (AE) may contribute to Cl(-) secretion by airway epithelial cells. However, the molecular identity, the cellular location, and the contribution of AEs to Cl(-) secretion in serous epithelial cells in tracheal submucosal glands are unknown. The goa...

OBJECTIVES To compare the efficiency of the subannular T-tube (SAT) vs that of the repetitive transtympanic Duravent tube (TTT) in children with recurrent or chronic otitis media (OM) with effusion or tympanic membrane retraction and to establish which population would be more likely to benefit from TTTs vs SATs. DESIGN Medical record review. SETTING Tertiary care pediatric center. PATIEN...

PURPOSE To investigate the relative involvement of chromatic and achromatic visual subsystems in central serous chorioretinopathy, and to correlate the function changes with the changes of the foveal photoreceptor layer using Fourier domain optical coherence tomography (FD-OCT). METHODS Central serous chorioretinopathy patients and control subjects were tested and compared. Equiluminant Chrom...

Serous cells are the predominant site of cystic fibrosis transmembrane conductance regulator expression in the airways, and they make a significant contribution to the volume, composition, and consistency of the submucosal gland secretions. We have employed the human airway serous cell line Calu-3 as a model system to investigate the mechanisms of serous cell anion secretion. Forskolin-stimulat...

Purpose: Retinal pigment epithelial detachments (PEDs) are characterized by a separation between the RPE and innermost aspect of Bruch's membrane. Many chorioretinal diseases can lead to detachment which most common is age-related macular degeneration; but significant number PEDs idiopathic in etiology. be classified as drusenoid, serous, vascularized, or fibrovascular type.
 Currently, se...

objective: e-cadherin is a classic cadherin that plays a key role in epithelial cell adhesion. this protein is being referred to as the suppressor of proliferation and invasion. limited studies have investigated e-cadherin expression in salivary gland neoplasms. this study sought to assess the expression of e-cadherin and its possible role in progression and invasion of salivary gland neoplasms...