total serum copper levels of 70 pregnant women hospitalized for delivery at misaghieh (private), 90 at farah (public) maternity hospitals immediately after delivery and 27 non-pregnant women (control) were measured. the copper level in the blood serum of umbilical cord of the newborn infants was also determined. the copper levels were significantly elevated in both pregnant groups as compared t...

in our previous studies we have evaluated the role of antioxidants and trace elements in potentially malignant disorders and cancers of the oral cavity, taking into consideration the importance of antioxidants as biomarkers in cancer detection. we felt that other than evaluation, the correlation and interdependence that existed among antioxidants and trace elements require further evaluation in...

Primary chronic forms of copper poisoning have been reported to occur in goats around the copper industries in Kerman province. The survey was carried out from autumn 2015 to the end of summer 2016, in Kerman province, Iran. Based on clinical signs, confirmed by necropsy and copper concentration of serum and different tissues, ten live chronic copper poisoned (CCP) goats were used in the study ...

Biliary excretion is the major elimination route of copper, therefore increased hepatic copper concentrations could be caused by cholestasis. Hepatic copper accumulation is cytotoxic and results in fibrosis in hepatic tissues. Aim: The aim of this work is to determine the concentration of copper in serum and hepatic tissue in infants with cholestasis and its impact on liver function tests. Subj...

backgroundmany studies reported that copper, zinc and magnesium play important roles in the pathogenesis and development of neonatal hyperbilirubinemia. exchange transfusion and intensive phototherapy are known two modalities of therapy for severe neonatal hyper bilirubinemia, but the effect of them on those trace elements is unknown.materials and methodscopper, zinc and magnesium serum levels ...

background: copper and zinc are the elements with numerous physiological activities.  copper  (cu)  has  an  important  role  in  angiogenesis  and  acts  by increasing vascular endothelial growth factor (vegf). serum levels of copper will be increased in cancer incidence, progression and recurrence. the aim of this study was to measure blood levels of copper, zinc, and the ratio of cu /zn, as ...

Introduction: Iron deficiency anemia is recognized as the most prevalent nutrient deficiency in the world and iron supplements, which are prescribed daily in pregnant women for prevention of this anemia, may have unfavorable effects on copper absorption. The purpose of this study was to determine the effects of iron supplementation on serum copper status of pregnant women. Materials and Methods...

Serum copper, caeruloplasmin, iron, iron-binding capacity, and antioxidant activity were measured in 120 normal subjects and in 189 patients with rheumatoid arthritis. Both serum copper and serum caeruloplasmin were significantly raised in rheumatoid disease in both sexes. A significant inverse relation was found between serum iron and serum copper, and a strong direct correlation between serum...

Background: In acute lymphoblastic leukemia (ALL) the bone marrow loses its ability in the differentiation and maturation of blood cells at different stages. Zinc and copper are important co-factors for several enzymes and play an important role in maintenance of DNA integrity. Changes in serum levels of zinc and copper have been found in lymphoproliferative disorders. In the present study, the...

background: pemphigus vulgaris is a life threatening, blistering skin disease. it is an autoimmune abnormality. due to involvement of oral cavity and pharynx, patients are at risk of nutrients deficiency. the aim of this study was to evaluate the status of selenium, copper, and zinc in these patients. methods: in a case-control study, 43 newly diagnosed pemphigus vulgaris patients were compared...