OBJECTIVE: Level of serum homocysteine is remarkably common among patients with moderate to sever renal failure. We assessed whether serum homocysteine concentrations were correlated with proteinuria in overt diabetic nephropathy. MATERIALS AND METHODS: A cross-sectional study was carried out on 45 patients (29 males, 16 females) with overt proteinuria. All subjects had type 2 diabetes. Data i...

The effect of endotoxemia on renal function was studied in 76 orthotopic liver transplant patients. In the preoperative period, a high preoperative serum creatinine level (> 2.0 mg/dl) was significantly associated with postoperative endotoxemia. The serum total bilirubin level was significantly greater in the patients with high serum creatinine levels than in those with lower serum creatinine l...

BACKGROUND/AIM We assess the impact of serum creatinine at baseline on complete remission rate and long-term outcome in severe lupus nephritis (SLN). METHODS A total of 86 adult patients with SLN [International Society of Nephrology/Renal Pathology Society (ISN/RPS) class IV lesions] were evaluated based on baseline serum creatinine levels (≤1.0, 1.01-1.5, 1.51-2.0, 2.01-3.0, and >3.0 mg/dl; ...

this study evaluates the effect of preoperative increased level of serum creatinine (cr) on early outcomes after coronary artery bypass graft surgery (cabg). 1140 patients who underwent cabg in our center were studied. patients with cr >2.25 mg/dl or preoperative dialysis and who had off-pump operations were excluded. group 1 consisted of 892 patients with normal cr (0.5-1.2 mg/dl) and group 2 ...

BACKGROUND Chronic kidney disease (CKD) is a major public health problem that may lead to end-stage renal disease (ESRD). Renal transplantation has become the treatment modality of choice for the majority of patients with ESRD. It is therefore necessary to monitor the disease progression of patients who have undergone renal transplantation. In order to monitor the disease progression, the conti...

them to "make the most of the limited time left." Parents vividly remembered the doctor's response to their distress. The doctor's ability to accept and understand the parents' grief was important in establishing trust and shaping the future relationship. Feelings of anger, guilt, and sadness are well known to be part of the process of grieving, which may begin at the time of diagnosis when the...

The aim of this study was to observe the effects of uric acid lowering therapy (UALT), febuxostat and allopurinol, on blood pressure (BP) and serum creatinine level. Post-hoc data were derived from a phase-III, randomised, double-blind, 4-week trial of male gouty patients that compared the safety and efficacy of febuxostat and allopurinol in adults with gout. The subjects were randomly assigned...

objective(s) oxidative stress plays an important role in diabetic nephropathy pathogenesis. rosmarinic acid, a plant phenolic compound, was first used as an antioxidant agent for inhibition of diabetic nephropathy. material and methods forty male rats were uninephrectomized from the left flank.the rats were divided in four groups randomly; group one as control, group two diabetic untreatment, g...

objective: level of serum homocysteine is remarkably common among patients with moderate to sever renal failure. we assessed whether serum homocysteine concentrations were correlated with proteinuria in overt diabetic nephropathy. materials and methods: a cross-sectional study was carried out on 45 patients (29 males, 16 females) with overt proteinuria. all subjects had type 2 diabetes. data in...