background: spontaneous ovarian hyperstimulation syndrome rarely occurs during pregnancy and is usually associated with high levels of human chorionic gonadotropin, in conditions such as molar or multifetal pregnancies. case report: here we report spontaneous ovarian hyperstimulation in a patient presenting with missed abortion at 16th week of gestation, when serum ß-subunit human chorionic gon...

placental site trophoblastic tumor (pstt) is the rare variant of gestational trophoblastic diseases (gtd), which differs histologically and immunologically from gtd. diagnosis of pstt is often difficult and delayed. in most cases, diagnosis is not possible until the surgery is performed. the most therapeutic choice is hysterectomy and it is usually successful. here we report two cases of pstt.

INTRODUCTION We describe a case of non-small cell lung cancer that was found to stain positive for beta-human chorionic gonadotropin on immunohistochemistry. Only a few case reports have described lung cancers that secrete beta-human chorionic gonadotropin. CASE PRESENTATION A 68-year-old Caucasian man presented with symptoms of weakness, fatigue and weight loss for the past two months. On ex...

malignant neoplasms (MNP). The frequency of PNS in MNP ranges from 1 to 20 % according different authors. One the manifestations is acne, which occurs against background neoplasm due hormonal disorders. presented article describes a clinical case patient with mixed germ cell tumor and metastases retroperitoneal lymph nodes. produced human beta-chorionic gonadotropin, led development acne as PNS...

The paper titled “The Effects of Fetal Gender on Serum Human Chorionic Gonadotropin and Testosterone in Normotensive and Preeclamptic Pregnancies” [1], published in Journal of Pregnancy, has been retracted as it is found to contain a substantial amount of material from the paper “Human chorionic gonadotropin and testosterone in normal and preeclamptic pregnancies in relation to fetal sex,” auth...

OBJECTIVE This study was undertaken to compare from a societal perspective the costs of systemic methotrexate administration with those of laparoscopic salpingostomy for the treatment of patients with tubal pregnancy. STUDY DESIGN An economic evaluation was set up in tandem with a multicenter randomized clinical trial that compared systemic methotrexate administration and laparoscopic salping...

Human granulosa cells cultured with calf serum actively proliferated for 18-20 generation and secreted progesterone into the medium; progesterone levels appeared to decline with increase in generation number. Cells cultured under serum-free conditions secreted significant amounts of progesterone and insulin-like growth factor II (IGF-II). The progesterone secretion was enhanced by the addition ...

BACKGROUND In screening for Down's syndrome in the second trimester of pregnancy, the concentrations of alpha-fetoprotein, the beta subunit of human chorionic gonadotropin, and intact human chorionic gonadotropin in material serum are widely used markers. We investigated a new marker, dimeric inhibin A, and compared its predictive value with that of the established markers. METHODS Serum samp...

Human chorionic gonadotropin (hCG) is useful in evaluating and monitoring early pregnancy as well as trophoblastic disease. Here we describe the management of women with elevated serum human chorionic gonadotropin in a case of a 51-year-old female who was unsuccessfully treated for ectopic pregnancy. She was subsequently diagnosed with pituitary hCG production, which should be considered as dif...

Background and Aims: Some nanoparticles can be used in immunoassays to increase sensitivity. This study aimed to evaluate a novel nano-immunoassay based on bovine serum albumin nanoparticles (BSA NPs). Materials and methods: At first, the nanostructure was synthesized, and then applied as a tag in the nano-immunoassay. Then the concentration of β-subunit of human chorionic gonadotropin ...