the most accepted method of secondary prophylaxis in rheumatic fever (rf) has been an injection of 1,200,000 units of benzathine penicillin g (bpg) every 4 weeks, but recurrences have been reported in some patients despite such a prophylaxis program. the who recommended bpg injections every 3 weeks in high risk patients and situations due to some published data in favor of inadequacy of once ev...

regarding the high prevalence of hyperlipidaemia, which is one of the major risk factors of cardiovascular disease, and uncertain reports about the relation between periodontal disease and serum lipid profile, this study was conducted to assess this relation. the historical cohort study was conducted on 52 cases including 26 persons with chronic periodontitis as case group, and 26 healthy subje...

the relation between serum osmolality, glucose, sodium, bicarbonate, arterial ph, bun and level of consciousness was studied in 189 patients with diabetic ketoacidosis (dka). there was much overlap between all laboratory values among various groups, even when there was a statistically significant difference. to find a better predictor, we defined a new factor as serum osmolality/arterial ph. th...

background: it seems that serum vitamin d levels are one of the potential environmental factors affecting the severity of multiple sclerosis (ms). in this study, we aim to evaluate vitamin d levels in ms patients and healthy subjects and assess the relationship between vitamin d level and disability. methods: in this case-control study, 168 rapid relapsing ms patients and 168 matched healthy co...

the previous large retrospective studies demonstrated that treatment with statins reduces both the incidence of prostate cancer by 50% and serum prostate specific antigen (psa) level up to 40%. however the main problem in those studies was the absence of control groups of men with hypercholesterolemia without statin treatment. we performed a small prospective controlled clinical trial to assess...

chronic obstructive pulmonary disease (copd) has been defined by the global initiative for chronic obstructive lung disease (gold), as a disease state characterized by airflow limitation which is not fully reversible. copd consists of emphysema which is the destruction and inflammation of the lung alveoli. adenosine deaminase (ada, e.c.3.5.4.4) converts adenosine to inosine. there are two isoen...

purpose : to investigate intraocular pressure (iop) changes due to different serum level heights by using tonopen in acquired globes from the iran eye bank (ieb). methods : in this interventional prospective case series, serum were infused into 18 normal globes acquired from ieb by using 21g needle inserted in vitreal space through optic nerve head to change the iop by different fluid level hei...

background : ruptured cerebral aneurysms (icas) are the most common non-traumatic cause of subarachnoid hemorrhage (sah) that is associated with life threatening complications such as vasospasm, infarction, and hydrocephalus (hcp). the active participation of macrophage/monocyte-mediated inflammatory response in the pathogenesis of cerebral aneurysm as labeled with monocyte chemoattractantprote...

The recent report, “Serum prolactin level in psoriasis”, is very interesting 1. Ghiasi et al. concluded that “it seems that while intracutaneous prolactin may contribute to the pathogenesis of psoriasis, the probable role of pituitary-produced circulating prolactin in the disease process needs further investigation .” There are some concerns on this report. First, although Ghiasi et al. have st...

conclusions graft failure is more likely to occur in patients with higher serum creatinine levels. results there was a positive association between the serum creatinine level and graft failure (hr = 5.13, p < 0.001). a one unit increase in the serum creatinine level suggests an increased risk of graft failure of up to 5.13 times. the serum creatinine level significantly decreased over time (95%...