Elevated serum cholesterol and triglyceride is well established as a risk factor development of arteriosclerosis and coronary heart disease. A number of clinical studies have shown that reducing elevated levels of serum cholesterol and triglyceride, by drugs or dietary intervention, could lead to reduction in the incidence of coronary-related deaths. The search for new drug with the potential t...

Rats fed a fat-free diet containing no drug, 0.02% or 0.10% halofenate, or 0.25% clofibrate for 14 days were injected intravenously with equivalent amounts of either [2-3H]glycerol or [1(3)-3H]glycerol. Blood samples were collected at times up to 150 min after injection and serum triglycerides were isolated and assayed for radioactivity. Kinetic analysis of the serum appearance and clearance cu...

Background   Lipoprotein lipase activity can be increased by clofibrate. Clofibrate is used to reduce serum triglyceride level in adults. The aim of this study was to determine the effect of clofibrate on serum triglyceride and cholesterol level after administration of intravenous lipid in very low birth weight neonates. Method In a randomized double blind placebo – controlled study, 60 very lo...

To investigate the relationship between serum lipids and alkaline phosphatase during normal pregnancy, we measured triglyceride, total cholesterol, HDL-cholesterol, and LDL-cholesterol concentrations and alkaline phosphatase activity in serum samples from 546 apparently healthy pregnant, postpartum, and nonpregnant women. Serum HDL-cholesterol levels did not change significantly during pregnanc...

to evaluate the effects of season, sex and age on serum concentrations of thyroid hormones, cholesterol and triglyceride, and their correlations together in dromedarian camels, these parameters were measured in 180 clinically healthy dromedary camels. no significant difference was detected for the measured serum parameters between the two sexes and among the different age groups of camels and n...

To evaluate the effects of season, sex and age on serum concentrations of thyroid hormones, cholesterol and triglyceride, and their correlations together in dromedarian camels, these parameters were measured in 180 clinically healthy dromedary camels. No significant difference was detected for the measured serum parameters between the two sexes and among the different age groups of camels and n...

Most clinical laboratories directly measure serum triglyceride, total cholesterol, and high- density lipoprotein cholesterol. They indirectly calculate low-density lipoprotein cholesterol value using the Friedewald equation. Although high serum triglyceride (>400 mg/dL or 4.52 mmol/L) devaluates low-density lipoprotein cholesterol calculation by using this formula, effects of low serum triglyce...