BACKGROUND The optimal arterial oxygen saturation in the first weeks of life is unknown for immature newborn infants. OBJECTIVES To determine the effect of targeting high versus low oxygen saturation in the first weeks of life on the outcome of very low and extremely low birth weight infants. METHODS Randomized and observational studies were sought that compared the outcomes in babies with ...

CONTEXT Low oxygen saturation appears to decrease the risk of severe retinopathy of prematurity (ROP) in preterm newborns when administered during the first few weeks after birth. High oxygen saturation seems to reduce the risk at later postmenstrual ages (PMAs). However, previous clinical studies are not conclusive individually. OBJECTIVE To perform a systematic review and meta-analysis to r...

report. New York: Oxford University; 2005. 4. Fortes Filho JB, Barros CK, daCostaMC, ProcianoyRS. Results of a program for the prevention of blindness caused by retinopathy of prematurity in southern Brazil. J Pediatr (Rio J). 2007;83:209-16. 5. Gilbert C, Fielder F, Gordillo L, Quinn G, Semiglia R, Visintin P, et al. Characteristics of infants with severe retinopathy of prematurity in countrie...

survival rate was significantly better in babies with apnea of prematurity (69.2%) as compared to those with infection and apnea (23.1%). When compared to infection (all cases) where the survival rate was 60%, infection with apnea had a significantly poorer outcome (p <0.05) indicating thereby that apnea is a manifestation of severe sepsis(4). Apnea of prematurity and fewer episodes (between 1 ...

Background: Necrotizing enterocolitis is one of the serious complications of prematurity. Eosinophilia has not been proposed as a classical laboratory abnormality in NEC. Previous studies suggest that eosinophilia during NEC may be a sign of allergic enterocolitis. Case presentation: We present a premature neonate with birth weight of 1280 grams with abdominal distention, bilious gastric resid...

Retinopathy of prematurity is one of the main causes of childhood blindness. Worldwide, there are more than 50,000 children blind due to retinopathy of prematurity. Visual impairment is a consequence of retinal detachment. It can be detected by serial ophthalmologic examination of infants at risk, and those identified with the severe form of the disease can be treated by laser or cryotherapy, w...

Background: Retinopathy of prematurity is a vascular retinal disease that can cause blindness in premature new born babies. Several risk factors are associated with the incidence of ROP. Information and data on risk factors associated with ROP in context to Nepalese population is scarcely documented in literature. Objectives: The purpose of this study was to evaluate the risk factors of retinop...