depression is a serious disorder in today’s society, with the estimates of lifetime prevalence being as high as 21% of the general population in some developed countries. as defined by the american psychiatric association, depression is a heterogeneous disorder often manifested with symptoms at the psychological, behavioral, and physiological levels. such patients are often reluctant to take sy...

a 73-year-old female patient developed a generalized tonic-clonic seizure on the 6th day after treatment with moxifloxacin 400 mg daily intravenously for appendicitis. this patient had atrial fibrillation and history of a surgery for intracerebral hemorrhage, with impaired renal function and liver function, but without history of seizures. moxifloxacin was discontinued and switched to cefuroxim...

background: the challenge of antiepileptic drugs (aeds) management is to attain the best compromise between the desire to maximize seizure control and the need to keep side‑effects within tolerable limits for the individual patient. to reduce devastation in iranian epileptic patients, the aim of this study was to explore the overall outcome following aeds prescription. methods: a cross‑sectiona...

Acute myopia following use of some drugs is a relatively rare condition. Topiramate prescribed for seizure prophylaxis is one of these drugs. In this paper a case of acute transient myopia after taking topiramate is reported. The reported patient is a 28-year old woman who had no history of any eye disease. Following consumption of topiramate pill for one week, she had found blurred vision ...

previous, intravenous immunoglobulin (ivig) has been used for treatment of patients with immunodeficiency. however, recent studies have shown that ivig is a suitable approach for treatment of inflammatory and autoimmune diseases. although the exact mechanism of ivig action is not well known, recent findings have demonstrated that ivig impacts on expression and function of fc receptors of immuno...

ôbjective: to compare the effectiveness and safety of the methylphenidate produced in ïran (stimdate®) with its original brand (ritalin®) in children with âttention deficit hyperactivity disorder (âdhd). methods: ïn this double-blinded randomized clinical trial, 30 patients with âdhd who were 6 to 16 years old, were divided into two groups: 15 in stimdate® and 15 in ritalin® group. the two grou...

objective: to compare side effects between users of two kinds of injectable contraceptives (depo-medroxy progesterone acetate and cyclofem). materials and methods: this cross-sectional descriptive study included 250 women, aged 18-40 years, using depo-medroxy progesterone acetate (dmpa) or cyclofem. the volunteers were examined six months after using contraceptive, and they were asked about fol...

conclusions administration of aeds in general and levetiracetam in particular should be based on attention to pharmacokinetic behavior in terms of monotherapy or polypharmacy. case presentation two cases were studied, one patient was a 32-year-old male and the other was a 14-year-old female. the key words relevant to search topics were surveyed using pubmed (united states national library of me...

the administration of b-interferon is a recognized treatment for multiple sclerosis. the frequency of side effects is an important factor in drug or product selection. in this study, the side effects of three available b-interferon products are compared in 122 multiple sclerosis patients who were treated with b-interferon products for at least three months and had the expanded disability status...

background: renal failure is an important adverse effect of drug poisoning. determining the prevalence and etiology of this serious side effect could help us find appropriate strategies for the prevention of renal failure in most affected patients. objectives: the present study is aimed to identify drugs that induce renal failure and also to find the prevalence of renal failure in patients refe...