Silymarin, an extract of the seeds of Silybum marianum L. (milk thistle), is used for treatment of liver diseases. It contains several active flavonolignans; the major are silybin, which is a mixture of diastereomers A and B, and silychristin. Low bioavailability of silybin and silychristin is related to low water solubility of these compounds. In order to enhance the solubility, S. marianum dr...

Introduction: This review focuses on the efficacy and safety of Iranian medicinal plants found effective in the management of diabetes in humans and animals. Material and methods: EMBASE, Scopus, PubMed, Web of Science, Google Scholar, and IranMedex databases were searched up to 8 October 2007. The search terms were “diabetes” and “plant”, “herb”, “traditional”, and “natural” or “herbal medicin...

Deve dikeni (Silybum marianum) tohumuna çözücü ile ekstraksiyon yöntemi uygulanarak %7,3 verimle silimarin tozu elde edilmiştir. Ekstrakte tozun %57,8 içerdiği bulunmuştur. Silimarin içeriği dikkate alınarak silybum marianum tohumunun %4,21 olarak Ekstrakt ve orjinal silimarin, Fourier dönüşümlü kızıl ötesi spektroskopisi (FTIR), Optik Mikroskop, X-ışını kırınımı (XRD) taramalı elektron mikrosk...

The balance between anti- and prooxidants in animal organisms general each cell particular is responsible for the regulation of many metabolic processes that provide immunocompetence, growth, development protection animals from oxidative stress, related to inflow cadmium plumbum. Therefore, objective our study was influence a liposomal drug based on interferon milk thistle (Silybum marianum (L....