In the present study, we have investigated the effects of silymarine on depression and the possible role of serotonergic system in these effects. The rats were anesthetized intraperitoneally with ketamine hydrochloride and placed in a Stoelting stereotaxic instrument. A stainless steel guide cannula (22-gauge) was implanted in the third ventricular region. The third ventricular region was infus...

In the present study, we have investigated the effects of silymarine on depression and the possible role of serotonergic system in these effects. The rats were anesthetized intraperitoneally with ketamine hydrochloride and placed in a Stoelting stereotaxic instrument. A stainless steel guide cannula (22-gauge) was implanted in the third ventricular region. The third ventricular region was infus...

Liver disorders may occur as a result of exposure to chemical compounds capable inducing the oxidative stress and hepatic injuries. The aim present study was investigate effects flower extracts B. Variegata for treatment liver injury induced by CCl4. About 1 ml/kg body weight (b.w) CCl4 experimental mice intraperitoneal way 14 days. methanol chloroform (100, 200 300 mg/kg b.w) were administered...

Ethanolic extract of root and root derived callus extracts of Premna serratifolia L were investigated against paracetamol induced oxidative stress and hepatotoxicity in blood and liver of male albino rats. The root explants were cultured on MS medium supplemented with various combination and concentration of plant growth regulators. The best callus biomass was observed from the MS medium supple...

silybum marianum, is known to have anti-inflammatory, hepatoprotective and anticarciogenic effects. the aim of this study was to compare effects of silymarin, rapamycin and fk506 on proliferation and apoptosis of human t cells stimulated with con a. peripheral blood mononuclear cells (pbmc) were stimulated with concavalin a  ( con a) (5µg/ml) and then treated with different inhibitors (silymari...