Introduction: Sinonasal malignancies are uncommon neoplasms with several histological subtypes. These malignancies have a poor prognosis and, because of the nonspecific nature of the symptoms, most patients are diagnosed late when the disease is already at an advanced stage. Therefore, most sinonasal malignancies tend to be treated with surgery and postoperative radiotherapy. Understanding the ...

Hepatocellular carcinoma (HCC) seldom presents only as acute visual loss without any other abdomen or systemic symptoms. Sinonasal area, besides, is an extremely rare metastatic site for HCC as well. We reported a rare case of a 69-year-old male, presenting initially with of left eye rapid vision loss, and the sinonasal mass lesion was found two months later when he had left epistaxis attacked....

BACKGROUND Adenoid cystic carcinoma (ACC) is a unique tumor characterized by frequent and delayed distant metastasis (DM) with uncommon regional lymph node metastasis. OBJECTIVES To evaluate the factors affecting DM of ACC and survival after appearance of DM. DESIGN A retrospective analysis of 94 cases of ACC from 1979 through 2001. SETTING Academic tertiary referral center. RESULTS Dis...

INTRODUCTION Metastatic disease in the sinonasal region occurs rarely and the primary site may be elusive. This case highlights the possibility of an occult renal tumor manifesting with nasal symptoms and the risk of severe bleeding following nasal biopsy. CASE PRESENTATION We report the case of a 79-year-old Caucasian woman who presented with a six-week history of intermittent left-sided nos...

OBJECTIVES/HYPOTHESIS To report on the clinical course and management of sinonasal paragangliomas (PGLs). STUDY DESIGN AND METHODS Retrospective chart review of six patients with PGLs of the nasal cavity and paranasal sinuses. RESULTS Three patients had tumors with malignant clinical behavior with cerebral metastases or infiltration of brain and local recurrence, despite surgery and/or radi...

We present our experience with sinonasal undifferentiated carcinoma at the University of Michigan over 13 years and review prior published data. We conducted a retrospective review of 19 patients who presented to a tertiary care academic center multidisciplinary skull base clinic with sinonasal undifferentiated carcinoma between 1995 and 2008. Overall survival was 22% at 5 years, and the estima...

Metastatic hepatocellular carcinoma (HCC) in the sinonasal region is rare. We report the case of a 45-year-old male hepatitis B carrier who had metastatic HCC 2 years after resection of the primary tumor. The patient died of terminal hepatic failure 6 weeks after the discovery of nasal septal metastasis. The clinical and histopathologic characteristics of the primary and metastatic hepatocellul...

Metastatic tumors to paranasal sinuses are exclusively rare. In this paper, we report a case of breast carcinoma metastasizing to the right maxilla. The metastasis occurred 5 years after radical mastectomy and presented as a primary sinonasal mass. The diagnosis was confirmed with histopathologic and immunohistochemical examination however the patient died before starting any specific treatment...

rhabdomyosarcoma is a common primary childhood malignancy that rarely metastasizes to the breast. we report a patient with a primary sinonasal rhabdomyosarcoma metastasizing to the breast, with no distant spread. we describe the imaging appearance of rhabdomyosarcoma on magnetic resonance imaging (mri), particularly on diffusion-weighted imaging (dwi) and apparent diffusion coefficient (adc) se...

Craniofacial resection is commonly performed in the surgical resection of sinonasal tumours involving anterior skull base. It entails a bicoronal scalp flap with lateral rhinotomy or an extended lateral rhinotomy to expose the anterior skull base. Transfacial approach is necessary in the resection of the nasal part of the tumour. The choice of surgical approach is based heavily on the surgeon's...