This paper describes certain changes in the heart frequency, which are produced by localized heating of various parts of the sinus venosus. It was formerly found by Gaskell (1) that the heating of the sinus venosus causes an acceleration while heating of atria and ventricle had no remarkable effect on heart rate. In this phenomenon, however, there are still some problems to be solved. One unset...

The presence of distinct electrophysiological pathways within the atrioventricular node (AVN) is a prerequisite for atrioventricular nodal reentrant tachycardia to occur. In this study, the different cell contributions that may account for the anatomical and functional heterogeneity of the AVN were investigated. To study the temporal development of the AVN, the expression pattern of ISL1, expre...

A 32-year-old man presented at the cardiology department for a routine check-up. He had no symptoms, particularly no cardio logical symptoms. Clinical examination and ECG revealed no abnormalities. Transthoracic echocardiography showed a mild dilatation of the right heart. Further functional evaluation of the right heart was performed with MRI to evaluate the presence of a left to right shunt a...

Nomenclature and Classification There are 3 major types of ASDs or interatrial communications: ostium secundum, ostium primum, and sinus venosus (Figure 1A) defects. The ostium secundum is a true defect of the atrial septum and involves the region of the fossa ovalis. The ostium primum defect is within the spectrum of the atrioventricular (AV) septal defects (Figure 1B; also known as AV canal d...

Nomenclature and Classification There are 3 major types of ASDs or interatrial communications: ostium secundum, ostium primum, and sinus venosus (Figure 1A) defects. The ostium secundum is a true defect of the atrial septum and involves the region of the fossa ovalis. The ostium primum defect is within the spectrum of the atrioventricular (AV) septal defects (Figure 1B; also known as AV canal d...

OBJECTIVE We would like to share our experience of surgical repair of sinus venosus atrial septal defect (ASD) using a simple "transcaval repair technique." METHOD Between January 2007 and October 2010, 48 consecutive patients of sinus venosus ASD underwent surgical repair using transcaval repair technique at our institute. Their ages ranged from 5 to 15 years and male to female ratio was 1.6...

A 13-year-old girl presented with clinical features of pulmonary stenosis and regurgitation. Haemodynamic studies suggested the presence of a right ventricular tumour. M-mode and two dimensional echocardiograms indicated one or probably two soft thin walled structures originating from the right atrium. At operation a persistent right sinus venosus valve was removed. One earlier case report desc...

We report the case of an asymptomatic six-year-old child with left atrial isomerism and sinus venosus atrial septal defect. The physical examination revealed several periods of bradycardia. During a 24-hour electrocardiographic monitoring the patient presented a significant sinus node dysfunction with sinus pauses of up to 2.4 seconds. A permanent pacemaker was implanted, with a satisfactory ou...

The liver exerts its influence in general cellular metabolism and homeostatic control within limits set by the quality and quantity of blood perfusing it. Hepatic outflow reflects hepatic portal flow which is influenced by the diverse blood flow requirements of other visceral organs engaged in metabolic and absorptive functions. In addition, the hepatic blood flow constitutes a sizeable fractio...