PURPOSE Development of an improved animal model for studying skin burns in rats. METHODS Twenty-four male Wistar rats were randomly assigned to four groups (n=6): G1-Control, G2- T100°C, G3-T150°C and G4-T200°C. Two 10 x 10 mm squares were outlined with a sterile surgical marker on each side and along the vertebral column using a prepared template positioned between the anterior and posterior...

Autologous skin-grafting is the gold standard for treatment of deep second and third degree burns. Available bioengineered skin products also necessitate this two-step surgical procedure. Therefore, we developed fetal skin constructs to improve healing of such degree burns. A bank of fetal skin cells was developed from one organ donation (4 cm2 of skin allowing the preparation of several millio...

Skin burns are common skin injuries that can result from exposure to various sources of heat by which, depending on the cause, different degrees of burns are generated. In restoration of superficial burns by re-epithelialization, the skin is rebuilt, but the skin color is different than the healthy tissue. Keratinocytes represent the major cells of the epidermis. These cells are sourced from ec...

background & aim: onosma stenosiphon has been used as herbal medicine for healing skin cuts and rashes. however, burn healing effect of this herb has not been yet reported in pharmaceutical texts. the aim of this study was to find out the effect of herb ointment on burn healing the superficial wounds post type ii burns of back and testis region in wistar rats. experimental: a total of 24 r...

Biobrane(®) is commonly used in paediatric burns to cover partial thickness burns and donor sites of split thickness skin (SSG). The purpose of this study is to evaluate the use of Biobrane(®) in dressing SSG adjacent to skin graft donor sites or partial thickness burns. A retrospective review was undertaken to determine the use of Biobrane(®) in dressing SSG, where the grafted areas were adjac...

BACKGROUND Treatment of burned patients is a tricky clinical problem not only because of the extent of the physiologic abnormalities but also because of the limited area of normal skin available. METHODS Literature indexed in the National Center (PubMed) has been reviewed using combinations of key words (burns, children, skin graft, tissue engineering, and keratinocyte grafts). Articles inves...

Background & Aim: Onosma stenosiphon has been used as herbal medicine for healing skin cuts and rashes. However, burn healing effect of this herb has not been yet reported in pharmaceutical texts. The aim of this study was to find out the effect of herb ointment on burn healing the superficial wounds post type II burns of back and testis region in Wistar rats. Experimental: A total of...

Two new techniques for investigating the thermal skinburn potential of airbags are presented. A reduced-volume airbag test procedure has been developed to obtain airbag pressures that are representative of a dynamic ridedown event during a static deployment. Temperature and heat flux measurements made with this procedure can be used to predict airbag thermal burn potential. Measurements from th...