There is now a plethora of evidence that children with sleep disordered breathing (SDB) show deficits in neurocognitive performance, behavioral impairments, and school performance. The following review will focus on the neurobehavioral impacts of SDB, pediatric sleep investigation challenges, potential mechanisms of behavioral and cognitive deficits in children with SDB, and the impact of SDB t...

BACKGROUND Nocturia has been independently associated with cardiovascular morbidity and all-cause mortality, but such studies did not adjust for sleep-disordered breathing (SDB), which may have mediated such a relationship. Our aims were to determine whether an association between nocturia and cardiovascular morbidity exists that is independent of SDB. We also determined whether nocturia is ind...

OBJECTIVE To explore the relationship between the prevalence of sleep disordered breathing (SDB) and face shape morphology in a large cohort of 15-year-old children. DESIGN Observational longitudinal cohort study SETTING Avon Longitudinal Study of Parents and Children (ALSPAC), South West of England. PARTICIPANTS Three-dimensional surface laser scans were taken for 4784 white British chil...

KEY POINTS Sleep disordered breathing (SDB) is common and the severity increases as pregnancy progresses.Frequent snoring, older age and high pre-pregnancy body mass index (>25 kg⋅m(-2)) could be reliable indicators for SDB in early pregnancy.SDB screening tools, including questionnaires, used in the nonpregnant population have poor predictive ability in pregnancy.Accumulating evidence suggests...

BACKGROUND Recent studies in children have demonstrated that frequent occurrence of parasomnias is related to increased sleep disruption, mental disorders, physical harm, sleep disordered breathing, and parental duress. Although there have been several cross-sectional and clinical studies of parasomnias in children, there have been no large, population-based studies using full polysomnography t...

PURPOSE Breathing sounds during sleep are altered and characterized by various acoustic specificities in patients with sleep disordered breathing (SDB). This study aimed to identify acoustic biomarkers indicative of the severity of SDB by analyzing the breathing sounds collected from a large number of subjects during entire overnight sleep. METHODS The participants were patients who presented...

Compelling data demonstrate a strong association between sleep-disordered breathing (SDB) and cardiovascular disorders. The association is most consistent between obstructive sleep apnea (OSA) and hypertension. Epidemiologic and clinic-based studies provide evidence for an etiological role of OSA in hypertension, independent of obesity. Furthermore, several studies suggest amelioration of hyper...

The ASD/OSA hypothesis as proposed in this paper will incorporate over 90 pieces of the "autism puzzle". It is suggested that the cause of autism is four-fold, requiring that: 1) the mother has sleep disordered breathing (SDB) during her pregnancy, 2) the infant is born with sleep disordered breathing, 3) both mother and infant have polymorphisms of the methylation pathway which are then trigge...

Sleep-disordered breathing (SDB) includes a wide range of breathing difficulties during sleep from primary snoring to obstructive sleep apnea (OSA) and its estimated prevalence is from 0.9% to 13% in children.1 Repeated partial (flow limitation, hypopnea) or complete (apnea) airway obstruction and increased respiratory effort are usually observed in subjects with SDB and these disrupted breathi...

1018 SLEEP DISORDERED BREATHING (SDB) IS A PREVALENT AND CHRONIC CONDITION THAT IS CHARACTERIZED BY RECURRENT EPISODES OF UPPER AIRWAY collapse during sleep. It is estimated that approximately 7% of adults in the general population have SDB of at least moderate severity.1 Several epidemiological and clinic-based studies have shown that the prevalence of altered glucose metabolism and type 2 dia...