Three patients with skin or muscle biopsy evidence of small vessel vasculitis presented with neurological symptoms: (1) frequent transient ischaemic attacks, (2) myalgia with encephalopathy, and (3) myalgia with marked weakness. The diagnosis of small vessel vasculitis needs consideration especially if presentation with polyneuropathy or cutaneous involvement is associated with elevation of ESR...

churg-strauss syndrome (css) is a small vessel granulomatous vasculitis that characteristically affects the middle age group and is extremely rare in children. we describe an 8-year-old girl with a prolonged history of cough and eosinophilia that initially was labeled as pulmonary tuberculosis, but after complementary assays, associated with skin biopsy, eosinophilic fibrinoid vasculitis, css w...

Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis encompasses 3 conditions: eosinophilic granulomatosis with polyangiitis (EGPA; formerly named Churg-Strauss syndrome), granulomatosis with polyangiitis (GPA; formerly named Wegener granulomatosis), and microscopic polyangiitis.1 Diagnosing ANCA-associated small-vessel vasculitis is challenging for clinicians because of its infrequ...

A common classification of cerebral vasculitis uses the size of the affected arteries and the etiology of the wall inflammation, but this classification scheme was established for systemic disease rather than cerebral disease [1,2,3,4]. Another way to classify cerebral vasculitis has been proposed by Kuker [4] dividing it into large vessel vasculitis (LVV), medium vessel vasculitis (MVV), and s...

Vasculitis is defined as inflammation directed at vessels, which compromises or destroys the vessel wall leading to haemorrhagic and/or ischaemic events. Skin biopsy is the gold standard for the diagnosis of cutaneous vasculitis, whose manifestations include urticaria, infiltrative erythema, petechiae, purpura, purpuric papules, haemorrhagic vesicles and bullae, nodules, livedo racemosa, deep (...

Small-vessel vasculitides associated with the presence of antineutrophil cytoplasmic antibodies in the serum are characterized by inflammation and necrosis of small vessels. A pauci-immune necrotizing crescentic glomerulonephritis typically occurs when there is renal damage. Pathogenesis of these diseases remains unclear although infectious, genetic and environmental factors have been involved....

The systemic vasculitides (SV) are a heterogeneous group of rare affections, characterized by a primary process of inflammation and damage of the vessel wall, resulting in blood flow impairment and, ultimately, in ischemia of the distal tissues. Pulmonary vasculitis usually is a component of a systemic small vessel vasculitis. Pulmonary vasculitides can be classified into three major groups: a)...