conclusions our findings showed that the genotype tt rs53576 oxtr, as well as t allele had significant differences in our population and play a protective role. therefore, it is suggested to place more interest on these oxtr in large populations and different ethnic groups. results the logistic regression analysis suggested no significant associations of oxtr single nucleotide polymorphism (snp...

background: several methods have been developed for detection of sequence variation in genes and each has its advantages and disadvantages. a disadvantage of them is that the simpler, cost-effective methods are commonly perceived as being less sensitive in their detection of sequence variation, whereas those with proven sensitivity have a requirement for complex or expensive laboratory equipmen...

the association of rs10818488 snp located in traf1/c5 region with rheumatoid arthritis (ra), has been picked up by genome-wide association studies. independent studies in different populations revealed inconsistent results. the aim of this study was to investigate the possible association of this snp with ra in iranian population. a total of 362 cases and 422 healthy controls were recruited in ...

some of the genotypes of cytokines are associated with acute graft versus host disease after bone marrow transplantation. the purpose of the present investigation was to find out the possible association between transforming growth factor beta-1 (tgf-β1) codon 25 polymorphism (rs:1800471) and acute graft versus host disease (agvhd) after bone marrow transplantation from the sibling with the sim...

background : we investigated whether the c-819t snp of the ctla4 gene is associated with type 1 diabetes (t1d) for the egyptian population, a multi-ethnic group.  we determined if expression of the c-819t snp correlated with onset of t1d for egyptian children and the prevalence of this polymorphism with respect to gender. methods: the association of the c-819t snp in intron 1 of the ctla-4 gene...

to assess the association between polymorphisms of the il-6 -174 g/c and behçet's disease (bd) in tunisian patients. dna was extracted from blood samples taken from 43 tunisian patients and 43 healthy controls. the polymorphisms were analyzed by pcr with the pcr-rflp. no significant association was found between patients and controls concerning polymorphism of il6 -174 g/c between the (allelic ...

The present study aims to examine the genetic variation of ATP1B1 gene concerning hypertension and chronic kidney disease CKD. (120 ) blood samples from participants were obtained divided into three groups: a first group representing hypertensive patients (hyper), second Hypertensive CKD (hyper with CKD), third control group. DNA was extracted all then converted cDNA ARMS-PCR technique used inv...

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