BACKGROUND Fluid overload in patients on conventional hemodialysis is a frequent complication, associated with increased cardiovascular morbidity and mortality. The dialysate sodium prescription is a potential modifiable risk factor. Our primary objective was to describe associations between dialysate-to-serum sodium gradient and parameters of fluid status. A secondary objective was to evaluate...

In acute renal failure (ARF) in the setting of a pediatric intensive care unit, most authors report the use of frequent cycles of (often low-volume) high-glucose solutions. That approach results in appropriate H2O ultrafiltration, but not in appropriate sodium removal, as a consequence of the sieving coefficient of sodium. That in turn leads not only to inefficient treatment of intravascular fl...

Low dialysate sodium concentrations have been associated with intradialytic symptoms such as muscle cramps and hypotensive episodes. High dialysate sodium concentrations lead to sodium loading, thirst and subsequent increase in interdialytic weight gain and hypertension. The optimal dialysate sodium concentration for an individual depends on the serum sodium concentration. The difference betwee...

Chronic left ventricular overload and left heart failure were produced by an aortic-left atrial shunt and superimposed aortic constriction. With the shunt alone, plasma renin activity and sodium balance were normal. Superimposed aortic constriction produced a further elevation in left ventricular end diastolic pressure (LVEDP), increased plasma renin activity and sodium retention occurred. Seve...

The structure of the title compound tris-odium aluminium bis-(arsenate), Na(3)Al(AsO(4))(2), is built up from AlO(4) and AsO(4) corner-sharing tetra-hedra, forming an undulating two-dimensional framework parallel to (100). The layers are constituted of large Al(6)As(6)O(36) rings made up from six AlO(4) and AsO(4) tetra-hedra in which two sodium cations are situated, the third sodium cation bei...

The search for the novel metal-organic frameworks (MOFs) materials using tetra-hydro-furan-2,3,4,5-tetra-carboxylic acid (THFTCA) as a versatile multi-carboxyl ligand, lead to the synthesis and the structure determination of the title compound, [Na(H(3)THFTCA)] or [Na(C(8)H(7)O(9))](n), which was obtained by a solution reaction at room temperature. The ligand is mono-deprotonated, coordinating ...

“If you have always done it that way, it is probably wrong.” —Charles F. Kettering, 1876–1958 The morbidity of decompensated heart failure is due to volume overload, a consequence of increased total body sodium.1,2 Failure to adequately reduce total body sodium contributes to progressive ventricular dysfunction, worsening heart failure, and excess morbidity. Ultrafiltration is the gold standard...