We thank Dr Mubareka and Dr Rubinstein for their thoughtful commentary [1] related to our recent publication on aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis [2]. We would like to provide some additional clarifications related to the formulation of colistin used in our study because the commen...

∗The authors would like to thank the Editor and a referee for some very thoughtful and constructive comments on an earlier draft of the paper. This research has been supported by Australian Research Council Discovery Grant No. DP0208333 and a Ph.D. Scholarship from the School of Business Systems, Monash University. All numerical results in the paper have been produced using the MATLAB software....

Acknowledgments We would like to recognize Elliot Sternthal, MD, FACE, and Joseph Vassalotti, MD, for their review of these guidelines and thoughtful comments.

Reflective thought (critical thinking) is essential to the medical student who hopes to become an effective physician. John Dewey, one of America's foremost educators in the early twentieth century, revolutionized critical thinking and its role in education. In the mid twentieth century Hannah Arendt provided profound insights into the problem of diminishing human agency and political freedom. ...

We would like to thank Professor Loh and Professor Gelman for their thoughtful comments. Some of the detailed points that the discussants bring up remind us to emphasize that in many regards our article offers only an overview of the scientific questions we aim to address and of the methods, models, and algorithms that we employ. Some technical details are omitted in the interest of readability...

The anatomical circuits for emotion are straightforward: prefrontal cortex, ventral striatum, and the amygdala. However, neurophysiologists have not yet uncovered any robust neurophysiological differences among what we perceive to be as radically different emotions. Nevertheless, they believe that someday, they will be able to discover local anatomical or physiological differences among our dif...