In this study, we performed high-resolution array comparative genomic hybridization with an array of 4153 bacterial artificial chromosome clones to assess copy number changes in 44 archival breast cancers. The tumors were flow sorted to exclude non-tumor DNA and increase our ability to detect gene copy number changes. In these tumors, losses were more frequent than gains, and gains in 1q and lo...

In this study, we performed high-resolution array comparative genomic hybridization with an array of 4153 bacterial artificial chromosome clones to assess copy number changes in 44 archival breast cancers. The tumors were flow sorted to exclude non-tumor DNA and increase our ability to detect gene copy number changes. In these tumors, losses were more frequent than gains, and gains in 1q and lo...

Invasive breast carcinoma of no special type (IBC NST) is a group malignant epithelial neoplasms the glands with highest incidence cancer in women. Tumor infiltrating lymphocytes (TIL) CD8+ considered T cells that play role reactivity specific immunity against cells. TIL component plays adaptive immunity. infiltration stromal tumor related to favorable prognosis and can predict therapy outcome ...

In this work we employ the Fourier Transform Raman Spectroscopy to study normal and tumoral human breast tissues, including several subtypes of cancers. We analyzed 194 Raman spectra from breast tissues that were separated into 9 groups according to their corresponding histopathological diagnosis. The assignment of the relevant Raman bands enabled us to connect the several kinds of breast tissu...

Breast cancer is a heterogeneous disease composed of multiple subtypes. Infiltrating ductal carcinoma (not otherwise specified-NOS) is the most common type. This study was designed to detect HER -2 expression by immunohistochemistry on routine sections of breast carcinoma cases and to compare it with the histological grading of ductal carcinoma.

background: breast cancer is the most common type of malignancy in the female population, rarely is reported by thromboembolic events during the course of the disease. in this case, we present a rare case of breast cancer presenting as deep vein thrombosis of the axillary vein.case presentation: a 40-year- old female was admitted due to pain and swelling of her right arm and forearm of two mont...

backgrounds: seminoma is frequently observed in human and canine testes especially in cryptorchids. canine and human seminomas are typically associated with leukocytic infiltration. objectives: we aimed to identify the type of lymphocytes that infiltrate to seminomas. methods: tumor infiltrating lymphocytes were evaluated by immunohistological techniques in 5 dogs with diffuse seminoma. routine...

conclusion non-mass-like lesions, lesions with focal or segmental distribution, with a “plateau” enhancement curve type were the most frequent findings of dcis lesions on mri. background adequate diagnosis of ductal carcinoma in situ (dcis) could lead to efficacious treatment. due to the fact that dcis lesions can progress to invasive carcinomas and that the sensitivity of the standard examinat...

BACKGROUND To determine in a large series of surgical biopsies, the frequency of various histologic types of primary solid malignant neoplasms in males and females in different age groups. METHODS A retrospective study of 20,000 consecutive surgical biopsies reposted in the section of histopathology, AKU in 2004. RESULTS Malignant neoplasms are commonest in the fifth and sixth decades of li...