Introduction: In Single Photon Emission Computed Tomography (SPECT), the projection data used for image reconstruction are distorted by several factors, including attenuation and scattering of gamma rays, collimator structure, data acquisition method, organ motion, and washout of radiopharmaceuticals. All these make reconstruction of a quantitative SPECT image very difficult. Simulation of a SP...

introduction: in single photon emission computed tomography (spect), the projection data used for image reconstruction are distorted by several factors, including attenuation and scattering of gamma rays, collimator structure, data acquisition method, organ motion, and washout of radiopharmaceuticals. all these make reconstruction of a quantitative spect image very difficult. simulation of a sp...

To improve SPECT reconstruction using spatiallycorrelated magnetic resonance(MR) images as a source of side information, one must account for mismatch between MRI anatomical information and SPECT functional information. We investigate an approach which incorporates the anatomical information into SPECT reconstruction by using region labels representing the anatomical regions extracted from MRI....

BACKGROUND xSPECT Bone® (xB) is a new reconstruction algorithm developed by Siemens® in bone hybrid imaging (SPECT/CT). A CT-based tissue segmentation is incorporated into SPECT reconstruction to provide SPECT images with bone anatomy appearance. The objectives of this study were to assess xB/CT reconstruction diagnostic reliability and accuracy in comparison with Flash 3D® (F3D)/CT in clinical...

Introduction: While the necessity of replacing voxels with blobs in conventional tomographic reconstruction based upon line-integrals is clear, it is not however well-investigated in plane- integral-based reconstruction. The problem is more challenging in convergent-plane projection reconstruction. In this work, we are aiming at utilizing blobs as alternative to voxels. <stron...

Introduction:Low-pass filters eliminate noise, and accordingly improve the quality of filtered back-projection (FBP) in the reconstruction of single photon emission computed tomography (SPECT) images. This study aimed at selection of an optimum low-pass filter for FBP reconstruction of SPECT images of small structures. Material and Methods:Sp...

Cardiac single photon emission computed tomography (SPECT) cameras typically rotate too slowly around a patient to capture changes in the blood pool activity distribution and provide accurate kinetic parameters. A spatiotemporal iterative reconstruction method to overcome these limitations was investigated. Dynamic rest/stress (99m)Tc-methoxyisobutylisonitrile ((99m)Tc-MIBI) SPECT/CT was perfor...

Introduction: We have investigated cardiac SPECT with slant hole collimator in which the holes are slanted towards the target organ, to provide greater sensitivity over the parallel hole collimator. In addition, parallel hole collimator was used to obtain a comparison in FWHM, sensitivity, Compton and photoelectric area values in the simulations. Materials and Methods...

As an alternative to the use of traditional parallel hole collimators, SPECT imaging can be performed using rotating slat collimators. A gain in image quality could be expected from the higher photon collection efficiency, however, the plane integral data measured by this type of collimator require a reconstruction to invert the three-dimensional (3D) Radon transform. The use of iterative metho...

An SPECT image can be approximated as the convolution of the ground truth spatial radioactivity with the system point spread function (PSF). The PSF of an SPECT system is determined by the combined effect of several factors, including the gamma camera PSF, scattering, attenuation, and collimator response. It is hard to determine the SPECT system PSF analytically, although it may be measured exp...