Objective: Assessment of spinal cord injuries (SCI) severity is usually done according to the International Standards for Neurological Classification Spinal Cord Injury (ISNCSCI). However, a limitation ISNCSCI has not been thoroughly evaluate; therefore, systematic review was performed gather current evidence on limitations assessing SCI.
 Methods: An extensive literature search using Medl...

Summary: Background: Patients with spinal cord injury (SCI) usually have permanent and often devastating neurologic deficits and disability and pain (1). According to the National Institutes of Health, "among neurological disorders, the cost to society of automotive SCI is exceeded only by the cost of mental retardation"(2). Neurogenic pain constitutes one of the enigmatic clinical sy...

Background & Aim: Patients with spinal cord injury (SCI) impose a heavy burden on health care system. Awareness on prevalence and incidence of SCI is important because this would show the necessity of prevention. This study aimed to investigate the epidemiology and types of traumatic spinal cord injuries in a trauma referral center in Guilan. Methods & Materials/Patients: This is a descripti...

Introduction: The use of standard rodent model, allows for the understanding of neuronal injury physiopathology and helping development of therapeutic strategies. Because of eliminating technical problems, we designed a modified impactor device with ability to induce different degrees according to kilodyne from very mild to very severe of spinal cord injury (SCI) and traumatic brain injury (TBI...

background: recent reports demonstrated that intravenous route as a minimally invasive method, similar to direct injection, is suitable for bone marrow stromal cell (bmsc) transplantation. in this study, we made a comparison of intraspinal and intravenous route of bmsc administration to repair injured spinal cord tissue. methods: six groups of adult female rats were used in this study. laminect...

BACKGROUND It is essential to use a definition that is precise and accurate for the surveillance of traumatic brain injuries (TBI) and spinal cord injuries (SCI). This paper reviews the International Classification of Diseases 10th revision (ICD-10) definitions used internationally to inform the definition for neurotrauma surveillance using administrative data in Ontario, Canada. METHODS PubM...

a spinal cord injury (sci) refers to any injury to the spinal cord or nerves at the end of the spinal canal that is caused by trauma instead of disease often causes permanent changes in strength, sensation and other body functions below the site of the injury. road traffic collision (rtc) or car crash occurs when a vehicle collides with another vehicle, pedestrian, animal, road debris, or other...

In the United States, about 10,000 people annually suffer spinal cord injuries (SCI). Eight thousand of those persons survive the acute injury period. In 1997, approximately 200,000 Americans were living with SCI. That number is increasing as the management of such injuries and their complications improves. Nonetheless, the life expectancies of patients with SCI remains substantially below normal.

A spinal cord injury (SCI) refers to any injury to the spinal cord that is caused by trauma instead of disease. Depending on where the spinal cord and nerve roots are damaged, the symptoms can vary widely, from pain to paralysis to incontinence. Spinal cord injuries are described at various levels of "incomplete", which can vary from having no effect on the patient to a "complete" injury which ...

We induced percutaneous spinal cord injuries (SCI) using a balloon catheter in 45 rats and transplanted human umbilical cord blood derived mesenchymal stem cells (hUCB-MSCs) at the injury site. Locomotor function was significantly improved in hUCB-MSCs transplanted groups. Quantitative ELISA of extract from entire injured spinal cord showed increased expression of brain-derived neurotrophic fac...