The clinical features in psoriatic arthritis straddle the divide between rheumatoid arthritis on the one hand and spondyloarthropathy on the other. The paper by Kruithof and colleagues compares synovial immunohistologic features and clearly identifies psoriatic arthritis as being a member of the spondyloarthropathy family.

OBJECTIVE To assess diagnostic implications of abnormalities of the pedal digital tufts and to identify features to facilitate distinguishing of spondyloarthropathy and leprosy. BACKGROUND Better criteria for distinguishing between these disorders are necessary if their character, natural history, and evolution are to be understood. METHODS Pedal x rays of 91 consecutive patients with diabe...

Infection is involved at each of these points. Clinical observations implicate bacterial infection in ReA. The principal gene associated with spondyloarthropathy is HLA-B27, and infection is the driving force behind HLA polymorphism. Observations in ReA and animal models suggest a central role for bacteria in pathogenic mechanisms. This article reviews current understanding of spondyloarthropat...

Here we describe two instances of pathological vertebral fusion in two genera of sauropodomorph dinosaurs from the Early Jurassic Lufeng Formation in Yunnan, China. The first is a specimen, of Lufengosaurus huenei with two fused cervical vertebrae, and the other is a specimen of the Lufeng basal sauropod, with two fused caudal vertebrae. Both pathologies are consistent with spondyloarthropathy ...

PURPOSE To study uveitis prevalence in the local population with spondyloarthritis and its temporal relationship with joint complaints. METHODS We reviewed seventy-seven charts of spondyloarthropathy patients from the rheumatology clinic of the "Hospital Universitário Evangélico de Curitiba" for spondyloarthritis class, patients' sex and age, occurrence of uveitis and its location and relatio...

Undifferentiated spondyloarthropathy (USpA) includes the forms that do not meet criteria for the established categories of spondyloarthropathy. The clinical spectrum of USpA is therefore wide and few studies have been published on USpA, especially peripheral arthritis. A total of 107 patients fulfilling the European Spondyloarthropathy Study Group criteria for SpA were studied retrospectively b...

Background: Spondyloarthropathies are a group of closely related inflammatory arthritis which involve the axial skeleton and are negative for rheumatoid factor. Objective: This case-control study was conducted to examine HLA- B27 positivity in patients with seronegative spondyloarthritis (SSA) as per ESSG criteria and compare the frequency with healthy controls because a lower positivity is rep...

Familial Mediterranean fever (FMF) is an autosomal recessively-transmitted disease characterised by attacks of fever and serositis. Articular involvement is the second most common manifestation following abdominal pain. Patients with FMF are considered to have an increased risk of sacroiliitis, while the association of such abnormalities with FMF has not been accepted uniformly. We report two c...

OBJECTIVE To investigate the potential role of the HLA-linked LMP2 (low molecular weight protein) gene polymorphisms in conjunction with DR4 and DR7 on extraspinal disease manifestations in HLA-B27 positive patients with spondyloarthropathy. METHODS 172 patients with spondyloarthropathy, 46 healthy, HLA-B27 positive blood donors, and 99 unrelated controls were typed for HLA-class I and II ant...