Design methodology and criteria to configure sprue bush for enhancing functionality is systematically compiled from plastic injection moulding machine perspective. Sprue conduit’s sensitivity to moulding objectives are quantitatively ghettoised as expansion ratio on the basis of ubiquitous empirical relationships. This generic, simple, inexpensive preventive criterion enables sprue bush conduit...

Water and electrolyte movement in the jejunum of normal subjects and patients with sprue was measured during perfusion with isotonic electrolyte solutions. Normal subjects absorbed water, sodium, and potassium. By contrast, in patients with sprue (seven with adult celiac sprue and one with tropical sprue) who had diarrhea and steatorrhea, these substances were secreted into the intestinal lumen...

In 10 southern Indian patients with tropical sprue, in vivo dialysis showed a defect of absorption of water and sodium from the rectum, when compared with 11 healthy volunteers. Sodium-potassium-ATPase activity, measured in homogenates of rectal biopsies, was significantly diminished in patients with sprue. Magnesium-ATPase and alkaline phosphatase were normal in biopsy homogenates. Decreased a...

Tropical sprue is an endemic condition in Puerto Rico, some Caribbean islands and Southeast Asia. It is characterized by diarrhea, poor appetite, weight loss and anemia. In recent years the incidence of tropical sprue has declined and the clinical picture is different. The supplementation of cereals and flours with folic acid for the prevention of neural tube defects in the newborns and to decr...

The cell population of the upper jejunal mucosa has been studied in cases of tropical sprue from the Far East and Middle East, and in similar cases arising in western Europe (;post-infective malabsorption'), and compared with cases of untreated coeliac disease and patients without small bowel disease.Infiltration of the epithelial layer of the upper jejunal mucosa by lymphocytes was found in tr...

Ashford (1917) and a number of subsequent workers regarded monilias, particularly Monilia psilosis, as the cause of sprue. Several species of the genus Monilia have been implicated in the causation of sprue and this disease was at one time regarded as moniliasis of the digestive tract. Although the result of recent work has shown that this view is no longer justifiable, there is a tendency for ...

AIM Tropical sprue was considered to be the most important cause of malabsorption in adults in India. However, several reports indicate that celiac disease is now recognized more frequently. METHODS We analyzed the clinical presentation, endoscopic and histological features of 94 consecutive patients (age >12 years) with chronic diarrhea and malabsorption syndrome. The spectrum of disease in ...

Celiac Sprue, a widely prevalent autoimmune disease of the small intestine, is induced in genetically susceptible individuals by exposure to dietary gluten. A 33-mer peptide was identified that has several characteristics suggesting it is the primary initiator of the inflammatory response to gluten in Celiac Sprue patients. In vitro and in vivo studies in rats and humans demonstrated that it is...

Manson in 1883 advocated the use of a folk remedy, liver soup, for the treatment of tropical sprue. Subsequently, with the development of morphological haematology, it was recognized that there were some similarities between tropical sprue and pernicious anaemia (Reed & Wyckoff, 1926). After Minot & Murphy (1926) demonstrated the effectiveness of liver therapy in pernicious anaemia, detailed st...