The developmental impact of selective serotonin reuptake inhibitor (SSRI) and other antidepressant treatments during gestation postpartum on anxiety depression behaviors in offspring is unclear. This review focuses how perinatal exposure to SSRI may have long term consequences for these affective early childhood beyond. Outcomes vary consideration given methodological factors related affects de...

PURPOSE Serotonin and the serotonin transporter have been implicated in the development of pulmonary hypertension (PH). Selective serotonin reuptake inhibitors (SSRIs) may have a role in PH treatment, but the effects of SSRI use on right ventricular (RV) structure and function are unknown. We hypothesized that SSRI use would be associated with RV morphology in a large cohort without cardiovascu...

Background. Selective serotonin reuptake inhibitor (SSRI) therapy complicates up to 10% of pregnancies. During therapy, SSRIs exert pleiotropic antidepressant, anorexigenic, and neurotrophic effects. Intrauterine SSRI exposure has been modeled by neonatal administration to developmentally immature rodents, and it has paradoxically elicited features of adult depression. We hypothesized neonatal ...

as the most common male sexual disorder premature ejaculation (pe), also referred to as early ejaculation (ee) or rapid ejaculation (re), affects 30%-40% of sexually active men. despite the limited number of available studies comparing the efficacy of selective serotonin re-uptake inhibitors (ssri) they have been thought to have beneficial effects for the treatment of patients with pe. in the p...

OBJECTIVE Recent data suggest that serotonin selective reuptake inhibiter (SSRI) medication is useful in preventing relapse in weight-restored anorexics. Our clinical impression has been that SSRIs are not effective in patients who are underweight with anorexia nervosa. METHOD In order to determine whether there was any benefit for SSRI medication in underweight anorexics, we compared two gro...

BACKGROUND The early years of life have a profound effect on a child's developmental pathway. The children born to mothers suffering from depression may be at risk of increased morbidity and mortality in the first years of life. OBJECTIVE The objective of this study was to investigate the hospital admissions and mortality of children whose mothers were dispensed a selective serotonin reuptake...