Methicillin-resistant staphylococci were tested for susceptibility to cephradine, cephaloridine, cephalexin, and cefuroxime and 30 degree C and 37 degree C on ordinary media and on media of enhanced osmotic strength. The coagulase-negative strains were divided into Staphylococcus epidermis and Staphylococcus hominis. Generally the number of susceptible strains decreased with low incubation temp...

Skin and soft tissue infections (SSTIs) can be defined as ‘an inflammatory microbial invasion of the epidermis, dermis and subcutaneous tissues’. 1 It is quite commonly encountered in clinical practice, encompassing a wide variety of presentations ranging from simple impetigo to life-threatening necrotizing fasciitis. The SSTIs are usually caused by Gram positive bacteria like Staphylococcus au...

Keratinocytes upregulate expression of endogenous antimicrobial peptides in response to inflammatory stimuli. We show that both viable and heat-inactivated Staphylococcus aureus and lipoteichoic acid differentially alter expression of these peptides upon contact with human keratinocytes. The findings indicate a diversity of staphylococcal factors involved in upregulation of antimicrobial peptid...

Staphylococcus aureus (S. aureus) is a common, Gram-positive species that is pathogenic in both human and animals. Rapid and direct identification of this bacterium specifically from clinical specimens would be useful in improving the diagnosis of S. aureus infections in the clinical microbiology laboratory. Although, some molecular identification assays are reported, some false-positive cases ...

Staphylococcus aureus and Staphylococcus epidermidis are two major skin associated bacteria, and Substance P (SP) is a major skin neuropeptide. Since bacteria are known to sense and response to many human hormones, we investigated the effects of SP on Staphylococci virulence in reconstructed human epidermis model and HaCaT keratinocytes. We show that SP is stimulating the virulence of S. aureus...

Staphylococcal scalded-skin syndrome is an exfoliative dermatitis characterized by the separation of the epidermis at the stratum granulosum. This disruption is mediated by one of two Staphylococcus aureus exotoxins, exfoliative toxins A and B (ETA and ETB). Both ETA and ETB have been reported to be bacterial superantigens. A controversy exists, however, as other data indicate that these exotox...

the objectives of this study were to define the clinical risk factors, microbiological spectrum, and visual outcome of bacterial keratitis at shahid sadoughi hospital (yazd, iran). a crosssectional prospective study, identified 80 cases of microbial keratitis from march 1999 to march 2001. inclusion criteria were presence of corneal stromal infiltrate in slit lamp examination, and microbiologic...

The study was carried out to isolate and characterize bacterial species from selected cafeterias in tertiary institution campus Ahmadu Bello University Zaria, Nigeria. A total of ten samples were for analysis which include; spoons, plates, forks, chopping boards, worktops, tables, hands, washing water, plate rinsing water1 water2. bacteriological using the nutrient agar (NA) media, prepared by ...