Objective: Although stevia leaf extract is an accepted sugar substitute that can contribute to improved caloric management and weight control, it also may enhance other aspects of human health. The effectiveness and safety of stevia leaf extract in these additional roles was evaluated. Methods: A detailed literature review was conducted and summarized. Results: An extract of the leaf of the her...

Stevioside is natural non-caloric sweetner isolated from Stevia rebaudiana BERTONI, which has been used as a non-caloric sugar substitute in Japan. Pezzuto et al. demonstrated that steviol shows a dose-dependent positive response in forward mutation assay using Salmonella typhimurium TM677 in the presence of metabolic activation system (Aroclor induced rat liver S9 fraction). Our studies were c...

Basic hydrolysis of a dichloromethane extract of Stevia lucida yielded (4R,5S,7R,9R,10R,11R)-7,9-dihydroxylongipin-2-en-1-one (1), which was oxidized and subjected to acidic conditions to generate the new seco-moreliane derivative 3. The structure of 3 was established based on NMR data interpretation and confirmed computationally. A plausible mechanism for the carbocationic rearrangement of the...

Purpose: The purpose of the study is to evaluate the antimicrobial and antitumor activities of Stevia rebaudiana (Asteraceae) leaf extracts. Methods: Four solvent extracts (ethyl acetate, acetone, chloroform and water) of Stevia rebaudiana leaves were investigated against Staphylococcus aureus, Salmonella typhi, Escherichia coli, Bacillus subtilis, Aeromonas hydrophila and Vibrio cholerae by us...

ANTIHYPERTENSIVE (BLOOD PRESSURE LOWERING) EFFECTS OF STEVIOSIDE, FROM STEVIA REBAUDIANA BERTONI, ON RATS, DOGS AND HUMANS – A SHORT REVIEW HIMANSHU MISRA1,2*, DARSHANA MEHTA1, B. K. MEHTA1* and D. C. JAIN2 1Natural Products Research Laboratory, School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain-456 010, Madhya Pradesh, India. 2Green Technology Department, Ipca Laborator...

Stevia rebaudiana, a perennial herb from the Asteraceae family, is known to the scientific world for its sweetness and steviol glycosides (SGs). SGs are the secondary metabolites responsible for the sweetness of Stevia. They are synthesized by SG biosynthesis pathway operating in the leaves. Most of the genes encoding the enzymes of this pathway have been cloned and characterized from Stevia. O...

Stevia rebaudiana Bertoni is a Paraguayan perennial antidiabetic herb belongs to Asteraceae family. The Leaves of stevia are about 300 times sweeter than sugar with no calories, that are the source of diterpene glycosides such as stevioside and rebaudioside A. Tissue culture is a rapid tool for propagation of stevia. In this research we studied the effect of different concentrations of mannitol...

low caloric sweeteners have been investigated to substitute sugar as an advantage for both nutritional and medicinal purpose. these sugar substitutes are interesting particularly for concepts marketed under a natural claim. among these, stevia rebaudiana is a small shrub; its leaves are used as a sweetener. serial dilution of the hot water crude extract of s. rebaudiana leaves and aqueous solut...

The inhibition for the corrosion of mild steel in sulphuric acid solution by the extract of Stevia rebaudiana leaves has been studied using electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization techniques. Inhibition was found to increase with increasing concentration of the leaves extract. The effect of temperature on the corrosion behavior of mild steel in 0.5M H2SO4 w...

Background: Despite the medicinal importance of Balanites aegyptiaca (L.) Del, Stevia rebaudiana (Bert.) Bertoni, Tylophora indica (Burm.f.) Merrill and Cassia sophera (Linn.), the antimicrobial potential of these plants has not been explored extensively, especially those of Cassia sophera. Methods: Both aqueous and alcoholic extracts of various parts of respective plants, and their in vitro ra...