نتایج جستجو برای: stromal cell

تعداد نتایج: 1706993  

Journal: :iranian biomedical journal 0
حجت اله عباس زاده hojjat-allah abbaszadeh تقی طریحی taki tiraihi علیرضا دلشاد ali reza delshad مجید صادقی زاده majid saghedi zadeh طاهر طاهری taher taheri

background: the present study investigated the functional maturity of oligodendrocyte derived from rat bone marrow stromal cells (bmsc). methods: the bmsc were isolated from female sprague-dawley rats and evaluated for different markers, such as fibronectin, cd106, cd90, oct-4 and cd45. transdifferentiation of olc from bmsc was obtained by exposing the bmsc to dmso and 1 µm all-trans-retinoic a...

Journal: :iranian biomedical journal 0
علیرضا خلعتبری ali reza khalatbary تقی طریحی taki tiraihi

background: recent reports demonstrated that intravenous route as a minimally invasive method, similar to direct injection, is suitable for bone marrow stromal cell (bmsc) transplantation. in this study, we made a comparison of intraspinal and intravenous route of bmsc administration to repair injured spinal cord tissue. methods: six groups of adult female rats were used in this study. laminect...

Journal: :basic and clinical neuroscience 0
soraya mehrabi sanaz eftekhari bfateme moradi hamdollah delaviz bagher pourheidar monir azizi

spinal cord injury (sci) is a debilitating disease which leads to progressive functional damages. because of limited axonal regeneration in the central nervous system, there is no or little recovery expected in the patients. different cellular and molecular approaches were investigated in sci animal models. cellular transplantation of stem cells can potentially replace damaged tissue and provid...

 Leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. They produce testosterone leading to hyperandrogenism. We present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra Sonography, and a rise of total and free serum testosterone. An ovarian source of androgen was suspected and a surgery performed. A diagnosis ...

Journal: :مجله دانشگاه علوم پزشکی شهید صدوقی یزد 0
مرتضی یافتیان m yaftiyan مژده صالح نیا m salehnia علی اکبر پور فتح اله aa pourfatollah

introduction: considering the importance of co-culture in differentiation of embryonic stem cells, the aim of this study was evaluation of the effect of co-culturing fetal liver stroma cells with p19 cells on the line of differentiation. materials and methods: for this purpose, p19 cells were cultured directly in semisolid medium. these cells proliferated and primarily differentiated to colonie...

Journal: :avicenna journal of medical biochemistry 0
hassan rafieemehr department of medical laboratory sciences, school of para-medicine, hamadan university of medical sciences, hamadan, ir iran maryam kheirandish department of immunology, blood transfusion research center, high institute for research and education in transfusion medicine, tehran, ir iran; department of immunology, blood transfusion research center, high institute for research and education in transfusion medicine, tehran, ir iran. tel: +98-218860150130, fax: +98-2188601555 masoud soleimani department of hematology, faculty of medicine, tarbiat modares university, tehran, ir iran; department of stem cell biology, stem cell technology research center, tehran, ir iran

conclusions taken together, the combination of chemical and growth factors in the two-step induction protocol may improve the efficiency of msc differentiation into neural progenitor cells, and may be a new method for the easy and fast application of mscs in regenerative medicine in the future. results the results of real-time pcr showed that the expression of the gfap, mbp, and map-2 genes aft...

Chobsaz F Khazaei M, Khazaei MR Rashidi Z

Background: Endometriosis is a benign hormone-dependent disease in women of reproductive age. There is no cure for eradicating the disease and there is need for new drugs. The aim of this study was to investigate the in vitro effect of noscapine as inducer of cell death on endometriotic stromal cells in patient's endometriosis in vitro. Materials and Methods: Endometrial biopsies from pati...

ژورنال: :مجله دانشکده پزشکی اصفهان 0
زهراالسادات مرتضوی دانشجوی پزشکی، کمیته ی تحقیقات دانشجویی، دانشکده ی پزشکی و مرکز تحقیقات فیزیولوژی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران شقایق حق جوی جوانمرد دانشیار، مرکز تحقیقات فیزیولوژی و گروه فیزیولوژی، دانشکده ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران مریم موتمر دانشجوی پزشکی، کمیته ی تحقیقات دانشجویی، دانشکده ی پزشکی و مرکز تحقیقات فیزیولوژی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران سعیده بحرانی دانشجوی پزشکی، کمیته ی تحقیقات دانشجویی، دانشکده ی پزشکی و مرکز تحقیقات فیزیولوژی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران فرید نصر اصفهانی دانشجوی پزشکی، کمیته ی تحقیقات دانشجویی، دانشکده ی پزشکی و مرکز تحقیقات فیزیولوژی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

مقدمه: از کارامدترین روش های ترمیم آسیب های بافتی، سلول درمانی است. امروزه از سلول های msc (mesenchymal stem cell) به دلیل قدرت بالای تمایز به انواع سلول ها و ترشح فاکتورهای رشد متعددی همچون pdgf (platelet derived growth factor) و sdf-1α (stromal cell-derived factors-1alpha) برای این منظور استفاده می شود. هورمون های جنسی با اثر بر میزان ترشح این فاکتورها، تکثیر و مهاجرت سلول ها و فرایند های ترم...

Ghanbari A Ghorbani R Khazaei M, Lotfi Kangarshahi R, Rashidi Z

Background: Noscapine is a water soluble alkaloid with antitussive property and very less toxicity. It is obtained from the Papaveraceae family. Recently, new pharmacological properties such as anticancer, anti stroke and anti-angiogenic effects are introduced. There is no scientific report on noscapine effect on reproductive system. The aim of present study was to determine in vitro effect of ...

Journal: :cell journal 0

introduction: there are the evidences to suggest that bone marrow stromal cells (bmscs) not only differentiate into mesodermal cells, but also adopt the fate of endodermal and ectodermal cell types. bmscs can be a valuable cell source as an autograph for clinical application involving regeneration of the central nervous system. bone marrow stromal cells can be expanded rapidly in vitro and have...

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