backgroud: protein-protein interaction, plays a key role in signal transduction in signaling pathways. different approaches are used for prediction of these interactions including experimental and computational approaches. in conventional node-edge protein-protein interaction networks, we can only see which proteins interact but ‘structural networks’ show us how these proteins interact which ca...

Sufficient cause interactions concern cases in which there is a particular causal mechanism for some outcome that requires the presence of 2 or more specific causes to operate. Empirical conditions have been derived to test for sufficient cause interactions. However, when regression outcome models are used to control for confounding variables in tests for sufficient cause interactions, the outc...

There is a large effort to map protein-protein interactions on a genome-wide scale. The utility of the resulting interaction networks depends on the reliability of the experimental methods and coverage of the approaches. Known macromolecular complexes provide a defined and objective set of protein interactions to which biochemical and genetic data can be compared and validated. We show a signif...

Currently, there is a major effort to map protein–protein interactions on a genome-wide scale. The utility of the resulting interaction networks will depend on the reliability of the experimental methods and the coverage of the approaches. Known macromolecular complexes provide a defined and objective set of protein interactions with which to compare biochemical and genetic data for validation....

today, organizations continuously try to find the ways to gain loyal customers because of their advantages. customer to customer interactions has attracted more attention among marketers in which customer-to-customer interactions has been known as one of the most important methods of creating loyal customers. the present paper seeks to propose a service model developed in traveling and tourism ...

The interaction between nano-SiO2 and lysozyme was investigated by the method of UV-Visible  detection and fluorescence spectroscopic techniques. The thermal denaturation of lysozyme has been investigated in the presence and absence of nano-SiO2 over the temperature range (293-373) K in different buffers and pH values, using temperature scanning spectroscopy. The presence of nano-SiO2 caused th...

The concept of business banking relationship, ie, the relations between banks and their client firms, as found in literature, is a poor conceptualisation of a rich and complex phenomenon whose structural, dynamic and organisational aspects are thus neglected. Most studies stress the operative and administrative issues whilst others looked at the relationships between banks and their customers a...

The structure-based design of small molecule modulators of protein-ligand binding and protein-protein interaction is a key component in drug discovery. The underlying protein interactions can be regarded based on structural similarity of the involved secondary structure elements [1]. The most prominent example is the protein fold of a protein domain that is more conserved than the amino acid se...