disease of unknown cause that can involve various organs. A diagnosis is usually made when clinical and radiological manifestations are supported by histological evidence of the presence of noncaseating granulomas in one or more tissues (1, 2). Sarcoidosis is well characterized by the presence of hilar lymphadenopathy and pulmonary infiltrates. Extrathoracic organs are also involved, such as th...

Adalimumab and other tumor necrosis factor-α inhibitors have been shown in the recent years to successfully treat sarcoidosis refractory to systemic corticosteroids and other agents.  However, there have been an increasing number of cases of sarcoidosis paradoxically induced by these agents.  It is hypothesized that this is due to the disruption of the fine balance of cytokines involved in gran...

The triad of rash, arthritis, and uveitis seems to be characteristic for early-onset childhood sarcoidosis. We describe an interesting case of early-onset childhood sarcoidosis coexisting enchondromatosis, which clinically masquerade as Langerhans cell histiocytosis. A 33 months old girl presented with skin rash, subcutaneous nodules with polyarthritis, and revealed the involvement of lymph nod...

Subcutaneous sarcoidosis (also known as 'Darier-Roussy sarcoid') is a cutaneous condition characterized by numerous deep-seated nodules on the trunk and extremities. Coexistence of sarcoidosis and breast cancer are reported in the literature, but there will always be a chance of misdiagnosis. It is very crucial to obtain a tissue diagnosis of suspicious metastatic lesions. We report a case of b...

Two unusual cases of sarcoidosis manifesting as subcutaneous masses of the face are reported: in the first, the lesion occurred at the site of an osteotomy for rhinoplasty and was the initial clinical manifestation of sarcoidosis; in the second, the skin lesion was part of a multisystemic disease. The cases were documented with CT. Sarcoidosis should be added to the differential of soft-tissue ...

We report a case of sarcoidosis with osseous involvement. Whole-body fluorine-18-fluorodeoxyglucose (FDG) PET scanning demonstrated multiple sites of FDG uptake in the hilar lymph nodes, right ulna, bilateral feet, and subcutaneous tissue of the extremities. FDG PET scanning provides useful information for the detection of sarcoidosis with systemic distribution, even when osseous lesions are in...