Tom, a 50-year-old man with metastatic pancreatic cancer, was referred by his phase I physician to our supportive care center for symptom management. He was initially diagnosed with pancreatic cancer involving the liver approximately 6 months before this visit. He developed progressive disease despite three lines of systemic therapy, including four cycles of gemcitabine and cisplatin, three cyc...

Results This patient presented to the emergency room with a respiratory infection. She had been feeling weak and had noticed tongue weakness and difficulty swallowing, which had worsened significantly since the respiratory infection. On examination she was found to have clinical signs of Right Middle Lobe pneumonia and was found to be weak, especially in her proximal muscle groups. She had bila...

Fetal acetylcholine receptor inactivation syndrome is a rare condition occurring in newborns of myasthenic mothers, characterized by bulbar and facial weakness after recovery from the generalized muscle weakness. Antibodies against fetal subunit of acetylcholine receptor seem to have a pathogenetic role leading to long-lasting injury in vulnerable muscle groups. We report a girl, born to a myas...

A recent outbreak of West Nile virus has allowed for observations as to the clinical course of this emerging pathogen during pregnancy. We present three cases of West Nile virus infection during pregnancy. Case 1 presented at term with focal subjective weakness and fever. With supportive care, her symptoms were resolved within 7 days, and she subsequently delivered an unaffected term infant. Ca...

Progressive muscle atrophy is a rare subtype of motor neuron disease that affects only the lower motor neurons and presents as asymmetrical rapidly progressive muscle weakness, atrophy and normal sensations. The diagnostic electrophysiological findings are denervation potentials in three out of four body segments (bulbar, cervical, thoracic and lumbosacral). The disease is fatal and the managem...

BOTULISM IS A POTENTIALLY FAtal, neuroparalytic illness resulting from toxins produced by the bacterium Clostridium botulinum. Human illness occurs as infant botulism, botulism from intestinal colonization and wound infections, and foodborne botulism. Symptoms appear approximately 12 to 36 hours after toxin exposure beginning with bulbar and autonomic nervous system disturbances. Descending, sy...

Guillain-Barré syndrome (GBS) is an acute peripheral neuropathy that develops as a result of post-infectious immune-mediated nerve injury. It can be classified into classic and variant GBS. Acute motor axonal neuropathy (AMAN) is a subtype of GBS with the key clinical features of pure motor weakness, areflexia, absence of sensory symptoms, and lack of neurophysiologic evidence of demyelination....

Neurological complication following Sinopharm vaccination is extremely rare and Guillain-Barre syndrome (GBS) among the least common complication. Here we report a case of 62-year-old male with GBS secondary to vaccination. A diagnosed patient schizophrenia presented three-day history lower limb weakness preceding sensation numbness. Nerve conduction study was suggestive GBS, lumbar puncture sh...

Background According to reports of the German Public Health Department, up to 80% of the children suffer on postural weakness. Most of them develop during the adolescent growth severe spine diseases like scoliosis. In case of slight postural deformity, patients are able to influence actively the posture of the spine by physiotherapy and training of stance and behaviour [1]. In advanced cases th...