Biochemical functionalization of surfaces is an increasingly utilized mechanism to promote or inhibit adhesion of cells. To promote mammalian cell adhesion, one common functionalization approach is surface conjugation of adhesion peptide sequences such as Arg-Gly-Asp (RGD), a ligand of transmembrane integrin molecules. It is generally assumed that such functionalization does not alter the local...

Lateral size, surface chemistry, and properties are varied in inorganic monolayers based on a transition metal-oxide. A variety of inorganic monolayers with their emergent properties have been studied in recent decades. However, it is not easy to tune the lateral size, surface chemistry, and dispersibility of monolayers by typical synthetic methods. In the present work, a new approach is develo...

Protein nanofibrils offer advantages over other nanostructures due to the ease in their self-assembly and the versatility of surface chemistry available. Yet, an efficient and general methodology for their post-assembly functionalization remains a significant challenge. We introduce a generic approach, based on biotinylation and thiolation, for the multi-functionalization of protein nanofibrils...

The near-field of surface plasmons is locally confined to nanometer dimensions. Here, we use surface plasmons to initiate polymer-functionalization of mesoporous silica films allowing subsequent ionic permselectivity gating based on polymer charge. We expect this functionalization approach to open a new dimension of functional miniaturization e.g. in nanofluidics.

Rapid and quantitative click functionalization of surfaces remains an interesting challenge in surface chemistry. In this regard, inverse electron demand Diels-Alder (IEDDA) reactions represent a promising metal-free candidate. Herein, we reveal quantitative surface functionalization within 15 min. Furthermore, we report the comprehensive effects of substrate stereochemistry, surrounding microe...

Surface functionalization and its potential application in different fields of science and technology make monolayer organic films attractive candidates as linkages between an underlying substrate and other molecular species. By now, self-assembled monolayers (SAMs) [1,2] generated from either alkanethiols (RSH) or disulfides (RSSR) (R= CnH2n+1), have become a practical tool for homogeneous sur...

In this work, we grow different types of carbon nanotube (CNT) forests directly on AlNbased electroacoustic biosensors and study their functionalization efficiency. CNTs are used to increase the effective surface area of the sensor, pursuing a better sensitivity, without increasing the sensor capacitance. Here we use a general method for CNT bio-functionalization with specific receptors for tar...

Surface chemical and biochemical functionalization is a fundamental process that is widely applied in many fields to add new functions, features, or capabilities to a material's surface. Here, we demonstrate that surface acoustic waves (SAWs) can enhance the chemical functionalization of gold films. This is shown by using an integrated biochip composed by a microfluidic channel coupled to a sur...