A 54-year-old man complained of burning pain, warm skin and erythema in his extremities. A diagnosis of primary erythromelalgia was made. Microneurography was used to clarify the role of skin sympathetic nerve activity in the pathophysiology of primary erythromelalgia. The patient showed normal skin sympathetic nerve activity but no vasoconstriction response. Aspirin activated the skin sympathe...

Sympathetic denervation is associated with many diseases. Most cutaneous external monitoring indicators are non-invasive and used widely in clinical medicine. The external monitoring indicators of sympathetic denervation are reviewed to facilitate the clinical diagnosis of sympathetic diseases and the results of sympathectomy. Useful indicators of sympathetic denervation include sweating, warm ...

BACKGROUND While erectile dysfunction is frequent among people with disorders of the spinal cord, the role of various clinical neurophysiological tests in assessment is not clear. AIMS To study the role of clinical neurophysiological investigations in assessing erectile dysfunction among men with spinal cord disorders. SETTING National Institute of Mental Health and Neurosciences, India. ...

The ability to recognize one’s own face is a hallmark of self-awareness. In healthy subjects, the sympathetic skin response evoked by self-face recognition has a greater area under the curve of the signal than responses evoked by other visual stimuli. We evaluated the sympathetic skin responses evoked by self-face images and by six other visual stimuli (conditions) in 15 patients with severe di...

WHAT KIND OF WORLD is it where some postganglionic sympathetic nerves secrete acetylcholine and where norepinephrine in conjunction with neuropeptide Y facilitates a key vasodilator response? It is the upside-down world of the human skin that possesses perhaps the most complex regional circulation in nature. Skin responds to environmental stimuli in ways that might be described as beautiful and...

It is more than a decade since scientists are making use of sympathetic skin response (SSR) as a clinical and research method to evaluate sympathetic nervous system. A major portion of the efferent pathway of this response is composed of non-myelinated nerves. Thus, the latency of the response may be significantly different in normal individuals with different height and limb lengths. This stud...

BACKGROUND AND PURPOSE Autonomic failure is known to manifest commonly in stroke, but very little attention has been given to various features of sympathetic dysfunction such as sudomotor dysregulation in cerebrovascular diseases. In the present study, our purpose was to assess quantitatively sympathetic reflex activity in brain infarction by measuring the sympathetic skin response. METHODS W...

The sympathetic skin response (SSR) is a change in skin potential following arousal stimulation, ®rst described by Tarchanoff (1890). SSR is a polysynaptic re ̄ex that is activated by a variety of afferent inputs. The ®nal efferent pathway involves preand postganglionic sympathetic sudomotor ®bers and ultimately activation of sweat glands by the sympathetic out ̄ow. The re ̄ex is coordinated in th...

Persons with seriously disabled speech organs and motor function have difficulty in speaking and communicating through hand gestures. Communication aids have been developed based on AAC (Augmentative and Alternative Communication) concept, and are being used to assist in the transmission of the user’s intention. However, the disabled person must have residual motor function to operate most of t...