how to cite this article: sorkhi h, salehi omran mr, barari savadkoohi r, baghdadi f, nakhjavani n, bijani a. csws versus siadh as the probable causes of hyponatremia in children with acute cns disorders. iran j child neurol. 2013 summer;7(3): 34-39.   objective there is a major problem about the incidence, diagnosis, and differentiation of cerebral salt wasting syndrome (csws) and syndrome of ...

The distribution of neuromyelitis optica (NMO)-characteristic brain lesions corresponds to sites of high aquaporin-4 (AQP4) expression, and the brainstem and hypothalamus lesions that express high levels of AQP4 protein are relatively characteristic of NMO. The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is one of the important causes of hyponatremia and results from an abn...

Hyponatremia is a marker of different underlying diseases and it can be a cause of morbidity itself; this implies the importance of a correct approach to the problem. The syndrome of inappropriate antidiuresis (SIAD) is one of the most common causes of hyponatremia: it is a disorder of sodium and water balance characterized by urinary dilution impairment and hypotonic hyponatremia, in the absen...

Syndrome of inappropriate antidiuretic hormone (SIADH) secretion is an endocrinological disorder which occurs when there evidence continued (ADH) in the absence appropriate osmotic volume stimulus. Most commonly it caused by different types cancer or medications (eg. diuretics, antidepressants, antipsychotics...). Secondary adrenal insufficiency insufficient adrenocorticotropic (ACTH) and corti...

Hyponatremia is considered to be a frequent complication of many clinical conditions [1]. Euvolemic dilutional hyponatremia caused by water retention in normal sodium stores has been termed as a syndrome of inappropriate antidiuretic hormone (SIADH) [2]. SIADH has been developed in patients with a variety of disorders, including central nervous system disorders, malignancy with autonomous ADH r...

We describe a 74-year-old man with rheumatoid arthritis (RA) who developed syndrome of inappropriate secretion of antidiuretic hormone (SIADH) 1.5 months after commencement of mizoribin prescription when his arthritis was improved. He noticed nausea and headache and serum Na fell as low as 118 mEq/l. Normal urinary Na excretion without hypotension or hemoconcentration negated the possibility of...

BACKGROUND AND OBJECTIVES The pathogenesis of hyponatremia (serum sodium <135 mEq/L) in Kawasaki disease (KD) remains unclear. We investigated the clinical significance of hyponatremia, and the role of interleukin (IL)-6 and IL-1β in the development of hyponatremia and syndrome of inappropriate antidiuretic hormone secretion (SIADH) in KD. SUBJECTS AND METHODS Fifty KD patients were prospecti...

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common cause of euvolemic hypo-osmotic hyponatremia. There are several etiologies of SIADH including neuroendocrine tumor, pulmonary disease, infection, trauma, and medications. Here, we report a case of SIADH associated with a schwannoma involving the mediastinum in a 75-year-old woman who presented with nausea, vomit...