background: systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. the importance of some genes in the development of systemic lupus erythematosus has been implicated. the gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has b...

Dear Editor, The article by Ji et al1 is very interesting. However, they do not mention the increased risk for systemic malignancies especially cutaneous malignancies in patients with sarcoidosis. The incidence of malignancies in patients with sarcoidosis is almost 1.65 times the incidence in patients without any clinical sarcoidosis.2 In fact, patients with sarcoidosis are almost 3 times more ...

Abstract Purpose of Review This review summarizes the most recent data on management small, node-negative Her2+ and triple-negative breast cancer. Recent Findings Both cancers are characterized by high rates recurrence worse survival outcomes compared to hormone-positive cancers. De-escalation systemic therapy in early-stage cancer is a national trend clinical research. prospective trials suppo...

objective: to evaluate the potentiality of ovcar–3 cell line of ovarian adenocarcinoma as a xenograft model for ovarian adenocarcinoma in nude mice. materials and methods: the cell line isolated from advanced human ovarian adenocarcinoma, were inoculated to eight nude mice and two months later. established tumors were transferred to pathology laboratory to be prepared by h&e; staining and immun...