The present study investigates whether transplantation of NSCs treated with T3 alone (T3/NSCs), or in conjunction with GDNF gene (GDNF-T3/NSCs), provides a better therapeutic effect than NSCs for chronic EAE. EAE rats were, respectively, injected with NSCs, T3/NSCs, GDNF-T3/NSCs, and saline at 10 days and sacrificed at 60 days after EAE immunization. The three cell grafted groups showed a signi...

This study was undertaken to determine T3 content in red cells by radioimmunoassay. T3 in red blood cells was solubilized fairly from the stroma by hemolysis and red-cell T3 content could be determined directly by radioimmunoassay of the lysate. After hemolysing red cells with an equal volume of distilled water, 0.4 ml of the hemolyzate was used for the assay. The red-cell T3 content was expres...

Side effects after the first administration of OKT3, a murine anti-CD3 monoclonal antibody (mAb) of the IgG2a class, are largely attributed to the release of cytokines as a result of T cell activation caused by interaction with Fc receptors (FcR) on human monocytes. As human monocytes possess FcR for murine IgG2a but not for IgA, it is expected that an anti-CD3 mAb of the IgA class causes less ...

Pronunciation variation is ubiquitous in the speech signal. Different models of lexical representation have been put forward to deal with speech variability, which differ in the level as well as the nature of mental representation. We present the first mismatch negativity (MMN) study investigating the effect of allophonic variation on the mental representation and neural processing of lexical t...

In Mandarin Chinese, the third tone (T3) is changed to the second tone (T2) or T2-like when followed by another T3 syllable in speech production. It has long been debated whether the production of a linguistic pattern like Mandarin T3 sandhi is operated via a computation mechanism or a lexical mechanism. The computation mechanism is that the sandhi/non-sandhi form of a tone is computed accordin...

Description: The objective of the tutorial is to survey recent algorithms and methodologies that have had (or are likely to have) a significant impact on the physical design industry. A second objective is to provide industrial feedback to the academic community in an effort to increase the relevance of academic research to industrial needs. Outline: Data Structures for VLSI, Partitioning, Floo...