BACKGROUND: The control of proliferation, differentiation and survival of normal and malignant cells in the tumour microenvironment is under the control of a wide range of different factors, including cell:cell interactions, cytokines, growth factors and hormonal influences. However, the ways in which these factors interact are poorly understood. In order to compare the effects of multiple vari...

The goal of this paper is to perform complex assembly tasks, using a robot assisted by a multi-axis vibrator that reduces friction and avoids jamming. An experimentbased approach using the Taguchi Method is applied to the tuning of the vibrator. The vibrators are tuned so that effects of friction and stick-slip can be minimized. Using actual assembly data and an experimental analysis method, ca...

abstract: the aim of this research is to propose a new approach of kansei engineering, kano model and taguchi design of experiments to identify, categorize and prioritize customersʹ emotional needs (kansei) in the automotive industry in order to more customer satisfaction. to achieve the above aim, first customersʹ kansei words identified and screened; then these words classified based on kano ...

In modern machining process, optimization technique is used to find the optimal values of input parameters and the effect of those parameters on response variables. If response parameters are more than one, Taguchi method of optimization may give different set of optimal levels for each response. In the present study, Taguchi-grey relational approach based multi response optimization has been u...

Bone drilling is a common procedure to prepare an implant site during orthopaedic surgery. An increase in temperature during such a procedure can result in thermal ostenecrosis which may delay healing or reduce the stability of the fixation. Therefore it is important to minimize the thermal invasion of bone during drilling. The Taguchi method has been applied to investigate the optimal combinat...

In this paper, the cutting of Tungsten Carbide ceramic using electro-discharge machining (EDM) with a graphite electrode by using Taguchi methodology has been reported. The Taguchi method is used to formulate the experimental layout, to analyse the effect of each parameter on the machining characteristics, and to predict the optimal choice for each EDM parameter such as peak current, voltage, p...

The multiobjective design of digital filters using the powerful Taguchi optimization technique is considered in this paper. This relatively new optimization tool has been recently introduced to the field of engineering and is based on orthogonal arrays. It is characterized by its robustness, immunity to local optima trapping, relative fast convergence and ease of implementation. The objectives ...

This paper presents the solution of economic power dispatch (EPD) through the application of genetic algorithm (GA) and the taguchi method. The economic power dispatch is a non-linear optimisation problem with several constraints. The objective of the proposed genetic algorithm combined taguchi method is to choose the most efficient combination of Pc (crossover probability), Pm (mutation probab...

Design of experiments (DOE) methods are very commonly used for process validation. In this study, we employed the Taguchi approach in order to develop an optimal process for the maximization of oscillatory shear stress environments (OSS). OSS has been associated with increase in cellular activity and has been linked to healthy gene expression and tissue formation. Therefore, OSS may be a key fa...