Tau is one of several types of microtubule-associated proteins (MAPs), responsible for the assembly and stability of microtubule networks that is present only in neurons and predominantly localized in axons which its functions are tightly regulated by phosphorylation. Via as yet unknown mechanisms, tau becomes hyperphosphorylated and accompanies with neuronal degeneration, loss of synapses...

A topoframe, denoted by $L_{ tau}$, is a pair $(L, tau)$ consisting of a frame $L$ and a subframe $ tau $ all of whose elements are complementary elements in$L$. $f$-ring $mathcal{R}(L_{ tau})$ is equal to the set $${fin Frm(mathcal{P}(mathbb R), L): f(mathfrak{O}(mathbb R))subseteq tau} .$$ In this paper, for every complemented element $ain L$ with $a, a'...

We first characterize $tau$-complemented modules with relative (pre)-covers. We also introduce an extending module relative to $tau$-pure submodules on a hereditary torsion theory $tau$ and give its relationship with $tau$-complemented modules.

we first characterize $tau$-complemented modules with relative (pre)-covers. we also introduce an extending module relative to $tau$-pure submodules on a hereditary torsion theory $tau$ and give its relationship with $tau$-complemented modules.

In this paper, we introduce the notions of expansion of ideals in $MV$-algebras, $ (tau,sigma)- $primary, $ (tau,sigma)$-obstinate  and $ (tau,sigma)$-Boolean  in $ MV- $algebras. We investigate the relations of them. For example, we show that every $ (tau,sigma)$-obstinate ideal of an $ MV-$ algebra is $ (tau,sigma)$-primary  and $ (tau,sigma)$-Boolean. In particular, we define an expansion $ ...

In this paper, for the first time, a comprehensive experimental study is performed on hydroforming process of metallic bellows. For this purpose, the effects of the main process parameters and their interactions on the characteristics of hydroformed metallic bellows are investigated using Response Surface Methodology (RSM). The selected parameters as input variables are internal pressure, die s...

‎let $r$ be a $*$-prime ring with center‎ ‎$z(r)$‎, ‎$d$ a non-zero $(sigma,tau)$-derivation of $r$ with associated‎ ‎automorphisms $sigma$ and $tau$ of $r$‎, ‎such that $sigma$‎, ‎$tau$‎ ‎and $d$ commute with $'*'$‎. ‎suppose that $u$ is an ideal of $r$ such that $u^*=u$‎, ‎and $c_{sigma,tau}={cin‎ ‎r~|~csigma(x)=tau(x)c~mbox{for~all}~xin r}.$ in the present paper‎, ‎it is shown that...

objective(s):alzheimer's disease (ad) is the most common age-related neurodegenerative disorder. one of the hallmarks of ad is an abnormal accumulation of fibril forms of tau protein which is known as a microtubule associated protein. in this regard, inhibition of tau aggregation has been documented to be a potent therapeutic approach in ad and tauopathies. unfortunately, the available syn...

objective(s):breast cancer is an important leading cause of death from cancer. stathmin and tau proteins are regulators of cell motility, and their overexpression is associated with the progression and bad prognosis of breast cancer. memantine, an n-methyl-d-aspartate (nmda) receptor antagonist, is the potential inhibitor of tau protein in neurons. this study determines the effect of memantine ...

tau is one of several types of microtubule-associated proteins (maps), responsible for the assembly and stability of microtubule networks that is present only in neurons and predominantly localized in axons which its functions are tightly regulated by phosphorylation. via as yet unknown mechanisms, tau becomes hyperphosphorylated and accompanies with neuronal degeneration, loss of synapses, abe...