(99m)Tc-Tin colloid is a commonly used colloidal radiopharmaceutical in human medicine for evaluating liver function and morphology. (99m)Tc-Tin colloid is taken up in the liver by the phagocytic activity of Kupffer cells, the reticuloendothelial cells of the liver. Unlike what occurs in human beings, we demonstrated (99m)Tc-Tin colloid uptake within the lungs and liver in healthy, mature, mini...

Colloidal particle size is an important characteristic that allows mapping sentinel nodes in lymphoscintigraphy. This investigation aimed to introduce different ways of making a (99m)Tc-tin colloid with a size of tens of nanometers. All agents, tin fluoride, sodium fluoride, poloxamer-188, and polyvinylpyrrolidone (PVP), were mixed and labeled with (99m)Tc. Either phosphate or sodium bicarbonat...

BACKGROUND: Radiosynovectomy is a therapy used to relieve pain and inflammation from rheumatoid arthritis and related diseases. In this study three 188Re particulate compounds were characterized according to their physico-chemical properties and their biological behavior in rabbits. The results were compared in order to establish which was the radiopharmaceutical that better fits the requiremen...

OBJECTIVE Gastrointestinal motility and functional motility disorders causing either delayed or accelerated gastric emptying (GE) may result in similar symptoms including nausea, vomiting, early satiety, fullness, bloating, and abdominal discomfort or pain. Hence, it is important to evaluate patients for both rapid and delayed GE in the same test. The gold standard technique to measure GE is sc...

introduction: sentinel lymph node biopsy is the standard procedure for lymph node staging in intermediate thickness melanoma. in iran, this procedure has not been addressed sufficiently. in this study, we report our experience in this area. methods: ten consecutive patients with intermediate thickness melanoma where included in our study. 1.5 mci of tc-99m antimony sulfide colloid in two divide...

BACKGROUND: Radiosynovectomy is a type of radiotherapy used to relieve pain and inflammation from rheumatoid arthritis. In this study, 188-Rhenium (188Re) colloids were characterized by physical and biological methodologies. This was used to assess which parameters of the kit formulation would be the basis in the development of a more effective radiopharmaceutical for synovectomy. Intraarticula...

introduction: there is a consensus in the literature that sentinel lymph node biopsy is the standard procedure for axillary staging in early stage (i and ii) breast cancer patients. usually during lymphoscintigraphy, the location of the sentinel lymph node is marked on the skin by an indelible ink. in this study we evaluated this issue in our patients. methods: 40 patients with the clinical dia...

Four different paddy soils collected around the Gyeongju nuclear site were treated with TcO4 solution under the assumption of two contrasting contamination scenarios. Scenario I (SN-I) is for a pre-transplanting deposition of Tc followed by plowing, whereas SN-II is for its deposition onto the water surface shortly after transplanting. Rice plants were grown in lysimeters in a greenhouse. Plant...

OBJECTIVES To determine the feasibility of sentinal lymph node (SN) radiolocalization and to assess the cost-effectiveness of the SN navigation surgery strategy in patients with stage N0 squamous cell carcinoma (SCC) of the head and neck. Patients Eleven consecutive patients with stage N0 SCC of the head and neck. METHODS Head and neck lymphoscintigraphy was performed 2 hours after the inject...