Bone scintigraphy has some limitations in detecting bone lesions at the time of diagnosis since Tc99m MDP scintigraphy does not trace lesions lacking osteoblastic activity3. Tc99m Sestamibi (MIBI) has been proposed as a potential tracer in patients with multiple myeloma, as its increased uptake in the bone marrow has been reported as an indicator of myeloma activity4. It has been suggested to b...

It has been established that a cationic gold(I)/(R)-DTBM-Segphos or (R)-BINAP complex catalyzes the atropselective intramolecular hydroarylation of alkynes leading to enantioenriched axially chiral 4-aryl-2-quinolinones and 4-arylcoumarins with up to 61% ee.

Dl-lsoleucine was complexed with Thioglycolic acid in the presence of Stannous ions to label with TC99m-Pertechnetate. Percentage labeling was determined by paper chromatography. Preparations of more than 95% labeled with Tc99m were injected to rabbits for imaging and tissue distribution studies. Tc99m.TGA.l LEU complex was investigated as a myocardial imaging agent with respect to its kinetics...

Four patients with sonographic suggestion of hepatic hemangioma are studied with Tc99m-labeled RBC scan. The scan findings are compaired with other imaging modalities. Lesions as small as 36 mm could be detected by this method. Tc99m labeled RBC scan is a valuable tool to differentiate hepatic hemangioma from other space occupying lesion of the liver.

Technetium labelled Sucralphate has been used as an ulcer scanning agent in the gastrointestinal tract. The labelling described in the literature involves incubation of Tc99m-HSA (Human serum albumin) with Sucralphate. Due to difficulty in obtaining HSA we used bovine serum albumin (BSA) to tag radioactivity with Sucralphate. The radioactive yields (Tagged Sucraiphate and Tc99m-BSA) obtained af...

We describe a case of a 58-year-old male with longstanding hypertension and Type 2 diabetes mellitus who developed sudden onset renal impairment. The first clue to the possible presence of amyloidosis in this case was provided by the radionuclide renal cortical scan performed with trivalent dimercapto succinic acid (Tc99m-DMSA-3), which revealed intense tracer uptake in the spleen suggesting am...

PURPOSE To explore the role of single-photon emission CT (SPECT) in initial diagnostic evaluation of patients with mild traumatic brain injury (MTBI) and to identify subgroups in which it may serve as a useful diagnostic tool. MATERIALS AND METHODS Patients with MTBI seen during a 14-month period were prospectively included in this study. All patients had a CT of head within 12 hours of injur...

BACKGROUND Infarct size is an important predictor of cardiac risk after acute myocardial infarction. The established modality for its assessment is Tc99m-Sestamibi Single-photon emission computed tomography (SPECT). In recent years, data are emerging demonstrating that scar size as assessed by late gadolinium enhancement in cardiovascular magnetic resonance imaging (CMR) as well as the presence...

BACKGROUND AND PURPOSE The clinical impact of facet joint bone scan activity is not fully understood. The hypothesis of this study is that facet joints targeted for percutaneous treatment in clinical practice differ from those with reported activity on technetium Tc99m methylene diphosphonate SPECT/CT. MATERIALS AND METHODS All patients with a technetium Tc99m methylene diphosphonate SPECT/CT...

BACKGROUND Controversy persists as to the need for both MIBG and bone scanning in routine evaluation of neuroblastoma. AIM To compare the efficacy of I-131- metaiodobenzylguanidine (MIBG) scan against that of conventional Tc99m- methylene diphosphonate (MDP) bone scan for the detection of skeletal deposition of neuroblastoma. METHODS AND MATERIAL The study included 57 patients (36 boys, 21 ...