UNLABELLED The performance of 99mTc Stealth liposomes was investigated in various rat models. METHODS Preformed polyethyleneglycol-containing liposomes with encapsulated reduced glutathione, were radiolabeled using the lipophilic 99mTc-HMPAO. The labeled liposomes were intravenously administered to rats with focal S. aureus or E. coli infection, or turpentine-induced inflammation. For compari...

Penangkapan non-osseous pada pemeriksaan sidik tulang dengan menggunakan radiofarmaka Technetium-99m methylene diphosphonate (Tc-99m MDP) dapat disebabkan karena proses neoplasma, trauma, inflamasi, iskemik, dan artefak. Perubahan metabolisme lesi diketahui pencitraan Tc-99m MDP. Lesi jaringan lunak terlihat adanya peningkatan aktivitas area fokal. Tujuan penulisan telaah pustaka ini adalah unt...

background: hormesis is defined as the bio-positive response of something which is bio-negative in high doses. in the present study, the effect of radiation hormesis was evaluated on the survival rate of immunosuppressed balb/c mice by cyclosporine a. materials and methods: we used 75 consanguine, male, balb/c mice in this experiment. the first group received technetium-99m (3700bq) and the sec...

introduction: monoclonal antibodies labeled mainly with 99mtc are being widely used as imaging agents in nuclear medicine. recently pr81 was introduced as a new murine anti-muc1 mab against human breast carcinoma. this antibody reacts with the tandem repeat of 20-mer peptide of protein backbone, and is of igg1 class, with an affinity of 2.19×10-8 m-1. due to high specific reactivity, this antib...

introduction: the aim of this study was to investigate the effect of methimazole on technetium-99m reabsorbing by thyroid gland , it may be possible to perform thyroid scan when the patients are on the methimazole, this can be time saving and decrease the adverse effects of discontinuing methimazole. patients and methods: among all the patients with hyperthyroidism who referred to nuclear medic...

The aim of this study was the investigation of absorbed dose to the kidneys, spleen, and liver during technetium-99 m ethylene dicysteine and technetium-99 m diethylenetriaminepentaacetic acid ((99m)Tc-EC and (99m)Tc-DTPA) kidney scan. Patients who had been prepared for the kidney scan, were divided into two groups (Groups 1 and 2). The first group (Group 1) and the second group (Group 2) recei...

A 72-year-old woman had insidious onset of heart failure, and was diagnosed as multicentric Castleman's disease. She underwent myocardial imaging with technetium-99m tetrofosmin, 1-123 beta-methyl-iodophenyl pentadecanoic acid (BMIPP). Technetium-99m tetrofosmin studies showed almost normal uptake of the left ventricular myocardium indicating normal myocardial perfusion. 1-123 BMIPP showed redu...

To study the scintigraphic detectability of cardiac rejection, we performed 135 planar myocardial scans ([99mTc]pyrophosphate, 85; 201Tl, 36; 67Ga, 14) together with endomyocardial biopsies in ten patients for a (mean) 17-mo postoperative period. Specificity of each agent exceeded 89%. Technetium-99m pyrophosphate showed results that significantly correlated with the severity of rejection (p = ...

The stability of the commonly used red cell radio labels chromium-51, indium-(111 or 113m), and technetium-99m, within intact red cells and stroma and their distribution within the cell were compared in undamaged and heat damaged red cells in relation to the clinical use of heat damaged cells in the assessment of splenic function. Chromium-51 labelled haemoglobin both in undamaged and heat dama...