نتایج جستجو برای: tendinopathy

تعداد نتایج: 2132  

2014
Dimitrios Stasinopoulos

Chronic patellar tendinopathy is a common clinical condition that is managed by physical therapists and is common among athletes and non-athletes alike. Patellar tendinopathy is characterized by the absence of inflammatory cells and prostaglandins and an increased presence of fibroblasts and disorganized collagen (1). Therefore, this condition is not inflammatory as physicians had thought but i...

Journal: :British journal of sports medicine 2012
J L Cook C Purdam

Tendons are designed to take tensile load, but excessive load can cause overuse tendinopathy. Overuse tendinopathy results in extensive changes to the cells and extracellular matrix, resulting in activated cells, increase in large proteoglycans and a breakdown of the collagen structure. Within these pathological changes, there are areas of fibrocartilaginous metaplasia, and mechanotransduction ...

Journal: :British journal of sports medicine 2017
Adrian Mallows James Debenham Tom Walker Chris Littlewood

OBJECTIVE Fear, anxiety, depression, distress and catastrophisation are all factors known to affect pain and disability levels. To date, the association of such psychological factors has yet to be established in tendinopathy. Therefore, the purpose of this paper was to determine if psychological variables are associated with tendinopathy and whether any such variables may be associated with pai...

Journal: :Molecular medicine reports 2015
Xinyu Cai Ming Cai Lieming Lou

Tendinopathy is a critical clinical problem as it is often asymptomatic at onset and during development, and is only recognized upon rupture of the tendon. It is common among recreational and competitive athletes. The present study sought to examine the molecular mechanism of the progression of tendinopathy by screening out differentially expressed genes (DEGs) and investigating their functions...

2014
Jessica Fairley Jason Toppi Flavia M Cicuttini Anita E Wluka Graham G Giles Jill Cook Richard O’Sullivan Yuanyuan Wang

BACKGROUND Patellar tendinopathy is a common cause of activity-related anterior knee pain. Evidence is conflicting as to whether obesity is a risk factor for this condition. The aim of this study was to determine the relationship between obesity and prevalence of magnetic resonance imaging (MRI) defined patellar tendinopathy in community-based adults. METHODS 297 participants aged 50-79 years...

2017
Soo-Hong Han Wonchul Choi Jiye Song Jaehee Kim Seungyong Lee Youngrak Choi Seong-Eun Byun Taekeun Ahn Heejung Ahn Catherine Ding Lloyd Baik Spencer Ward Kang Ting Soonchul Lee

It was reported that substance P had beneficial effects in the healing of acute tendon injury. However, the relationship between substance P and degenerative tendinopathy development remains unclear. The purpose of this study was to determine the role of substance P in the pathogenesis of tendinopathy. Healthy and tendinopathy tendon were harvested from human and tenocytes were cultured individ...

2016
Gev Bhabra Allan Wang Jay R. Ebert Peter Edwards Monica Zheng Ming H. Zheng

Lateral elbow tendinopathy, commonly known as tennis elbow, is a condition that can cause significant functional impairment in working-age patients. The term tendinopathy is used to describe chronic overuse tendon disorders encompassing a group of pathologies, a spectrum of disease. This review details the pathophysiology of tendinopathy and tendon healing as an introduction for a system gradin...

2017
Benjamin J.F. Dean Stephanie G. Dakin Neal L. Millar Andrew J. Carr

Tendinopathy is a common clinical problem and has a significant disease burden attached, not only in terms of health care costs, but also for patients directly in terms of time off work and impact upon quality of life. Controversy surrounds the pathogenesis of tendinopathy, however the recent systematic analysis of the evidence has demonstrated that many of the claims of an absence of inflammat...

2013
Brett D. Owens Jennifer Moriatis Wolf Amber D. Seelig Isabel G. Jacobson Edward J. Boyko Besa Smith Margaret A.K. Ryan Gary D. Gackstetter Tyler C. Smith Melissa Bagnell Gina Creaven Nancy Crum-Cianflone James Davies Nisara Granado Dennis Hernando Jaime Horton Kelly Jones Cynthia LeardMann William Lee Michelle Linfesty Gordon Lynch Hope McMaster Sheila Medina-Torne Amanda Pietrucha Teresa Powell Kari Sausedo Beverly Sheppard Katherine Snell Steven Speigle Martin White James Whitmer Charlene Wong

BACKGROUND Overuse injuries have a significant impact on United States military service members, but research to date has been limited in its ability to assess occupational and behavioral risk factors. HYPOTHESIS/PURPOSE To prospectively identify risk factors for the development of lower extremity tendinopathy and plantar fasciitis in United States military personnel. STUDY DESIGN Descripti...

2015
Jessica Pingel M. Christine H. Petersen Ulrich Fredberg Søren G. Kjær Bjørn Quistorff Henning Langberg Jacob B. Hansen Hazel RC Screen

BACKGROUND Achilles tendinopathy is a painful inflammatory condition characterized by swelling, stiffness and reduced function of the Achilles tendon. Kager's fat pad is an adipose tissue located in the area anterior to the Achilles tendon. Observations reveal a close physical interplay between Kager's fat pad and its surrounding structures during movement of the ankle, suggesting that Kager's ...

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