the antioxidant and cytotoxic properties of four major parts of methanolic extracts of tephrosia purpurea including leaves, root, stem and seed were investigated and compared. in vitro antioxidant activity of t. purpurea extracts was evaluated using 1,1-diphenyl-2-picrylhydrazyl (dpph), ferric reducing antioxidant power (frap), reducing power assay and antihemolytic assay. in vitro cytotoxic ef...

Microbial transformation of glabratephrin, the major isolated compound from Tephrosia purpurea, afforded pseudosemiglabrin. The formation of the transformed compound seems to be performed via ring opening-closure of a five-membered ring causing transformation from a spiro into a fused system. The structure of the transformed compound was determined by comprehensive NMR studies, including DEPT, ...

Two kinds of 'shapunkha', the 'Shvet' (white) and 'Rakta' (red) are described in some of the Ayurvedic texts and the former is reported therapeutically more effective. Some of the Ayurvedic physicians use T. villosa Pers. as 'Shvet sharpunkha' due to its persistently villous silky white parts. While others have advocated white colour of flowers as main feature for distinguishing "Shvet sharpunk...

Ethanol extract of leaves and flavonoid (isolated from leaves extract) from Tephrosia purpurea were evaluated for hepatoprotective activity in rats by inducing hepatotoxicity with carbon tetrachloride. These fractions were administered orally at a dose of 100 mg/kg/day. Serum level of transaminases, alkaline phosphate, and total bilirubin were used as biochemical markers of hepatotoxicity. Hist...

ABSTRACT Introduction Leaves of Tephrosia purpurea Linn (sarpankh), belonging to the family Leguminosae being used for the treatment of jaundice and claimed to be effective in many other diseases. The present research work was under taken to investigate the in-vitro antioxidant activity of aqueous and ethanolic extracts. Method The therapeutic effects of tannins and flavonoids can be largely at...

Aim: The present investigation has been conducted to evaluate the protective activity of Tephrosia purpurea extract (TPE) against arsenic induced toxicity. Materials and Methods: For this study, twenty four wistar albino rats were taken. Control group, group – I rats were given sodium arsenite @ 10 mg/kg and group – II rats were treated with TPE @ 500 mg/kg along with sodium arsenite @ 10 mg/kg...

Sorbents derived from roots of Tephrosia purpurea, leaves and stems of Terminalia Arjuna and Bivalve snail shells have been explored for their sorption abilities towards Methylene Blue using synthetically prepared simulated waste waters. It is found that at high pHs, these bio-materials have shown strong affinity towards Methylene Blue. The physicochemical properties such as pH, sorbent concent...