Submit Manuscript | http://medcraveonline.com reduced [3]. The reduction in fertility is documented in patients following orchidectomy with a contralateral viable testicle. In this case the contralateral testicle was atrophic following previous misdiagnosed torsion. Patients with severe testicular atrophy have undergone successful microdissection of sperm, in one study up to 56% of patients wit...

BMS-189453 is a synthetic retinoid that acts as an antagonist at retinoic acid receptors alpha, beta, and gamma. In Sprague Dawley rats at daily oral doses of 15, 60, or 240 mg/kg for 1 month, BMS-189453 produced increases in leukocyte counts, alkaline phosphatase and alanine aminotransferase levels, and marked testicular degeneration and atrophy at all doses. Significant overt signs of toxicit...

Background Testicular torsion is surgical emergency. Prompt diagnosis and treatment of testicular torsion is essential for testicular viability. At surgical exploration, the spermatic cord is seen twisted a variable number of times around its longitudinal axis. There is scant data regarding the degree of twisting and its association with testis outcomes. The purpose of our study is to explore h...

A rare case of a seminoma developing in an atrophic testis is described and the role of testicular atrophy in tumorigenesis is discussed. S. Ali Khan, Chief of Urology, Veterans Administration Medical Center, Northport, NY 11768 (USA) Introduction Testicular tumors are rare, accounting for less than 2% of all male malignancies. Testicular tumors occurring in atrophic testes are seen even less f...

A rare case of a seminoma developing in an atrophic testis is described and the role of testicular atrophy in tumorigenesis is discussed. S. Ali Khan, Chief of Urology, Veterans Administration Medical Center, Northport, NY 11768 (USA) Introduction Testicular tumors are rare, accounting for less than 2% of all male malignancies. Testicular tumors occurring in atrophic testes are seen even less f...

Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that has recently been found to cause fetal infection and neonatal abnormalities, including microcephaly and neurological dysfunction. ZIKV persists in the semen months after the acute viremic phase in humans. To further understand the consequences of ZIKV persistence in males, we infected Ifnar1-/- mice via subcutaneous injection of a ...

To observe the mechanism of alcoholic testicular damage, in a previous experiment we used weanling male SD rats aged 45 days, weighing about 200 g, and fed a liquid diet (Lieber's) containing 5% ethanol. The latter accounted for 36% of total caloric intake for 7 weeks, but did not result in testicular atrophy. In a later experiment, we used a liquid diet in which ethanol accounted for 46% of th...

Background: Ceftriaxone is an antibiotic used for treating respiratory,skin,bone and kidney infections. Our purpose was investigating effect of ceftriaxone on testicular tissue. Materials and Methods: 40 mice with 6 weeks old were used in this study. The mice randomly were divided into 2 groups, control- sham and test groups. The test group was subdivided to IP1 and IP2 which received Ceftriaxo...

Testicular torsion is a rare medical condition among neonates. Main symptoms are swelling, erythema and pain of the scrotum. It can be both perinatal (diagnosed at birth) postnatal after birth to 28 days life). If not treated, atrophy involving and/or contra lateral testis developed. Still being main treatment option surgery, new researches suggest delayed surgery in because low rates salvaging...

The secretion of androgens and estrogens by normal and abnormal testes was compared by determining the concentrations of dehydroepiandrosterone (DHEA), androstenedione (Delta(4)A), testosterone (T), estrone (E(1)), and 17beta-estradiol (E(2)) in peripheral and spermatic venous plasma samples from 14 normal men and 5 men with unilateral testicular atrophy. Four normal men and one patient with un...