Propylthiouracil (PTU) inhibits peripheral deiodination of thyroxine (T4) and triiodothyronine (T3) and decreases the metabolic effectiveness of T4 in animals. To assess the effect of PTU on extrathyroidal conversion of T4 to T3 in man, 15 studies were performed in athyreotic patients treated with 100 or 200 mug of L-T4 daily for 1 mo before the addition of PTU, 250 mg every 6 h for 8 days. se...

Abstract. We show that for any prime number l > 2 the minus class group of the field of the l-th roots of unity Qp(ζl) admits a finite free resolution of length 1 as a module over the ring Ẑ[G]/(1 + ι). Here ι denotes complex conjugation in G = Gal(Qp(ζl)/Qp) ∼= (Z/lZ)∗. Moreover, for the primes l ≤ 509 we show that the minus class group is cyclic as a module over this ring. For these primes we...

An insulin-mimetic compound (L-783,281) was used in an attempt to determine the role of the beta-cell insulin receptor (IR) on insulin release. Islets were isolated from C57Bl/6j mice and cultured for 1 to 4 days. Insulin release from individual islets perifused in the presence of 3 mmol/l glucose was 10.5 plus minus 1.4 pg/min. Addition of 10 micromol/l L-783,281 had no effect on the rate of i...

Background & Aims of the Study: In order to design membrane bioreactors (MBR) properly, it is essential to comprehend the behavior of microorganisms in such wastewater treatment processes. Materials & Methods: In this study, a lab-scale MBR process was operated to determine the biokinetic coefficients of the MBR system under different MLSS concentrations of 6800, 7000, 74...

Objective: We sought to test the hypothesis that the total QRS voltage without either set of the limb leads (I, II, III) or (R, L, F) may be a better indicator of LVH as compared to the total QRS voltage. Background: The total 12 lead QRS voltage has been a validated electrocardiographic criterion for left ventricular hypertrophy (LVH), with an upper limit of 175 mm. However, there is some redu...

A defect in transcapillary transport of insulin in skeletal muscle and adipose tissue has been proposed to play a role in the insulin resistance that leads to type 2 diabetes, yet the mechanism of insulin transfer across the capillary endothelium from plasma to interstitium continues to be debated. This study examined in vivo the interstitial appearance of insulin in hindlimb using the fatty ac...

RNA-dependent RNA polymerase from turnip crinkle virus-infected turnip transcribes both strands of a virus-associated satellite RNA, sat-RNA C (356 bases), in vitro. While both plus- and minus-strand sat-RNA C can direct the synthesis of full-length complementary-strand products, transcription of minus-strand RNA also generates two non-template-sized products, L-RNA and S-RNA (C. Song and A. E....

Plasma concentrations of amino acids are frequently elevated in insulin-resistant states, and a protein-enriched diet can impair glucose metabolism. This study examined effects of short-term plasma amino acid (AA) elevation on whole-body glucose disposal and cellular insulin action in skeletal muscle. Seven healthy men were studied for 5.5 h during euglycemic (5.5 mmol/l), hyperinsulinemic (430...

objective(s)                                                                                                                                                                               aim of the present study was to screen the antibacterial activities of some medicinal plants extracts traditionally used in azarbaijan area (iran). materials and methods thirty-six extracts obtained from differ...