Cauda equina syndrome is an unusual complication of ankylosing spondylitis. We present a case of a 68-year-old woman with long-standing ankylosing spondylitis who developed cauda equina syndrome. MRI revealed a characteristic widening of the lumbosacral thecal sac and numerous dorsal thecal diverticula. MRI is a powerful, noninvasive tool to confirm the diagnosis and exclude a treatable compres...

Fig . 1.A, CT scan. Epidural gas outlines thecal sac. 8, Anteroposterior radiograph of lumbar spine demonstrated, in retrospect , gas outlining thecal sac between L5 and 51 (arrows) . C, CT scan. Gas in left sacral foramen and in epidural space. D, CT scan. Soft-tissue mass (arrows) of heterogeneous density, interposed between rectum and coccyx, was thought to be phlegmon rather than frank absc...

Because IGFBP inhibit IGF-stimulated cellular proliferation and differentiation, it is hypothesized that variations among IGFBP in individual follicles might contribute to the regulation of recruitment, selection, dominance, and turnover of ovarian follicles. Sources of IGFBP in fluid of bovine follicles are not well established; thus, objectives of this study were to determine levels of IGFBP ...

The radiologic manifestations of lumbar disk herniation as seen on myelography, postmyelography CT, and, more recently , surface-coil MR have been well described (1-3). CT and MR findings of far lateral , extraforaminal disk herniation also have been reported (4]. Migratory fragments typically settle anterior and/or lateral to the thecal sac (5]. We report a case in which the sequestered migrat...

A new marine benthic, sand-dwelling Prorocentrum species from the temperate region of the Pacific coast of British Columbia, Canada, is described using LM and EM and molecular phylogenetic analyses. The cells have a broad oval shape, 40.0-55.0 μm long and 30.0-47.5 μm wide, and a wide U-shaped periflagellar area on the right thecal plate. The left thecal plate consists of a straighter apical ou...

Little is known about the role of activin B during folliculogenesis. This study investigated the expression levels of activin/inhibin subunits (βA, βB, and α), steroid enzyme, and gonadotrophin receptors in theca (TC) and granulosa cells (GC) by QPCR and activin A and B and inhibin A protein levels in follicular fluid (FF) of developing sheep follicles during estrus and anestrus. The effect of ...

During follicular atresia in the sheep and pig there is a marked reduction in the vasculature of the theca interna underlying the membrana granulosa. In the sheep there is no reduction of thecal blood vessels adjacent to the cumulus which remains viable. By contrast, in the pig the cumulus degenerates during atresia and the underlying thecal vasculature is greatly diminished. However, despite l...

Excess androgen synthesis by thecal cells is invariably detrimental to preovulatory follicles in the ovary and is considered a fundamental characteristic of polycystic ovary syndrome in women. Investigators have long postulated that granulosa cell-derived estrogens modulate thecal cell steroidogenesis via a short negative-feedback loop within the follicle. To test this hypothesis, we assessed t...

Activation of trkA, the nerve growth factor (NGF) tyrosine kinase receptor, has been recently implicated in the process of mammalian ovulation. During the hour preceding follicular rupture, a marked increase in trkA and NGF gene expression occurs in thecal-interstitial cells of the ovary. Immunoneutralization of NGF actions or pharmacological blockade of trkA transducing activity inhibits ovula...