Epilepsy is a common public health problem and needs multi-disciplinary treatment. Therapeutic drug monitoring (TDM) is one of step of the multi-disciplinary treatment in epilepsy at Epilepsy clinic, Khon Kaen University (Thailand). The TDM service has been established since 2008. Here, we aimed to study the roles of TDM order and epilepsy control. This is a prospective descriptive study in whi...

Biologic drugs have revolutionised many medical conditions. Like all medicines there is a role for therapeutic drug monitoring (TDM) with some agents in The utility of TDM biologic will be explored, covering methods detection as well the evidence that effective or otherwise.

Therapeutic drug monitoring (TDM) is the clinical practice of measuring specific drugs at designated intervals to maintain a constant concentration in a patient's bloodstream, thereby optimizing individual dosage regimens. It is unnecessary to employ TDM for the majority of medications, and it is used mainly for monitoring drugs with narrow therapeutic ranges, drugs with marked pharmacokinetic ...

concerns about increasing bacterial resistance to vancomycin, have caused the adult treatment guidelines to recommend higher trough concentrations based on the type and location of infectious disease. although these recommendations are not specific to children, the values can be extrapolated. this prospective study was designed to evaluate efficacy of current vancomycin dosing recommendations t...

BACKGROUND Therapeutic drug monitoring (TDM) is a useful tool for preventing Adverse Drug Events related to patient variability or inappropriate dosing. Typical physicians find proper interpretation of monitoring data difficult, however.' Patient follow-up by TDM experts is an effective method of improving TDM utilization, but the cost of having such a service track all patient visits across an...

Therapeutic Drug Monitoring In article number 2206753, Nathalia O. Gomes and Paulo A. Raymundo-Pereira report on personalized therapeutic drug monitoring (TDM) for subjects upon intake of acetaminophen oral pill tracking alterations in the analgesic concentration through changes oxidation current target naturally secreted saliva. The non-invasive method is made directly collected saliva at elec...

sirolimus is a potent immunosuppressive agent administered as prophylactic agent to prevent rejection after organ transplantation. sirolimus must be used within a narrow therapeutic window. due to inter- and intra-variability, sirolimus blood concentrations may be affected, therefore, there is no possibility of predicting the sirolimus blood concentrations based on the dose patients received. t...

Introduction Efficacy and safety of antidepressant drug therapy may be limited by inter-individual differences in concentration. Accounting for this inter-individuality, Therapeutic Drug Monitoring (TDM) enables clinicians to adjust dosage based on individual information concentration attained blood. However, research the basic assumption TDM, association between effect, has yielded ambiguous r...

Therapeutic drug monitoring (TDM) of psychotropic drugs such as antidepressants has been widely introduced for optimization of pharmacotherapy in psychiatric patients. The interdisciplinary TDM group of the Arbeitsgemeinschaft für Neuropsychopharmakologie und Pharmakopsychiatrie (AGNP) has worked out consensus guidelines with the aim of providing psychiatrists and TDM laboratories with a tool t...