among the therapeutic options for achalasia are pneumatic dilatation (pd), an appropriate long-term therapy, and botulinum toxin injection (bt) that is a relatively short-term therapy. this study aimed to compare therapeutic effect of repetitive pneumatic dilation with a combined method (botulinum toxin injection and pneumatic dilation) in a group of achalasia patients who are low responder to ...

Background: Basal Cell Carcinoma (BCC) is the most common type of skin cancer in human beings. Photodynamic therapy (PDT) is a novel therapeutic method which may be regarded as a non-invasive useful alternative for traditional treatments of BCC. This study was designed with the aim of evaluating the primary response of BCC to PDT.Methods: This clinical trial was perform...

conclusions it was concluded that the efficacy of tramadol and fluoxetine in males with premature ejaculation are the same and both are effective. both of these drugs are safe to treat premature ejaculation. results thirty-six subjects with the mean age of 44 ± 19.3 years underwent analysis. eighteen subjects were treated by fluoxetine and 18 by tramadol. the efficacy of treatment in the two gr...

glutamate-mediated excitotoxicity and neurodegeneration have been shown as pathophysiological hallmarks of multiple sclerosis (ms) and other autoimmune inflammatory cns disorders. n‑methyl‑d‑aspartate (nmda) receptors play a pivotal role in the mediation of neuronal glutamate excitotoxicity leading to cellular damage and apoptotic cell death. current treatment approaches targeting glutamate exc...

goldfish carassius auratus were subjected to either formalin (250 ppm) or nacl (10 ppt), over a 0.5-h period followed by 24-h freshwater exposure. serum biochemistry was monitored before exposure (0), immediately after (0.5) plus 3 and 24 h after exposure. results showed that both formalin and nacl treatments caused rapid increase in cortisol with a peak at 3 h, which did not recover until 24 h...

Background and objective:Breast cancer is the most common malignancy among women. The Neoadjuvant chemotherapy is the treatment of choice for non-operable tumors. The Ki67 is a proliferation marker that can be used to predict the therapeutic response to chemotherapy and the patients' prognosis. Methods: This retrospective study was carri...

we evaluated the effect of vitamin e and metformin on fatty liver disease in obese children.this interventional study has been done on 119 children with non-alcoholic fatty liver disease (based on sonography results). patients were divided into four treatment groups; they received metformin 1gr daily (age 12 years), vitamin e 800 u daily and vitamin e 400 u daily. liver sonography was performed...

Introduction: LiF dosimeter has the most application in medicine. This study aimed to evaluate some dosimetric properties of a novel LiF: Mg, Ti. Materials and Methods: An ELEKTA Precise linear accelerator was used to calibrate dosimeters at 6 MV. In this survey, responses of dosimeters were evaluated up to 1000 cGy. Background effect was investigated in two different dosimeter states includin...